When to start antibiotic therapy in patients with sepsis in the ICU?

According to the recommendations of the Surviving Sepsis Campaign (SSC), antibiotics should be administered within 1 hour after the onset of sepsis, and the centers for Medicare & Medicaid Services prescribe their administration within 3 hours.The objective of this publication is to analyze...

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Main Authors: V. A. Rudnov, A. U. Lekmanov, V. A. Bagin, M. N. Аstafieva
Format: Article
Language:Russian
Published: New Terra Publishing House 2020-11-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
Online Access:https://www.vair-journal.com/jour/article/view/467
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author V. A. Rudnov
A. U. Lekmanov
V. A. Bagin
M. N. Аstafieva
author_facet V. A. Rudnov
A. U. Lekmanov
V. A. Bagin
M. N. Аstafieva
author_sort V. A. Rudnov
collection DOAJ
description According to the recommendations of the Surviving Sepsis Campaign (SSC), antibiotics should be administered within 1 hour after the onset of sepsis, and the centers for Medicare & Medicaid Services prescribe their administration within 3 hours.The objective of this publication is to analyze the literature data on the start time of ABT when a patient with sepsis is admitted to the ICU.Results. Currently, basing on literature analysis, it is impossible to conclude about advantages of administering an antibiotic within an hour after the patient with sepsis is admitted to a medical unit. In the vast majority of cases, an antibiotic should be administered up to three hours of the early IT complex (bundle). The change in the time algorithm for drug administration is due to the heterogeneity of the clinical situation, the lack of the unified "scenario" of interaction between the infection and host, and the need for more detail diagnostics.Conclusion. It is preferable to approach each case individually when deciding about the time to start ABT, considering the history, clinical and laboratory characteristics by the admission to the ICU. However, ABT should be started within 3 hours in any case.
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institution Kabale University
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2541-8653
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publisher New Terra Publishing House
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series Вестник анестезиологии и реаниматологии
spelling doaj-art-32278fdddd914b3aad5dede2b3eae0ec2025-08-20T03:42:47ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532020-11-01175627010.21292/2078-5658-2020-17-5-62-70407When to start antibiotic therapy in patients with sepsis in the ICU?V. A. Rudnov0A. U. Lekmanov1V. A. Bagin2M. N. Аstafieva3Municipal Clinical Hospital no. 40; Ural State Medical UniversityInstitute of Clinical Surgery by Pirogov Russian National Research Medical UniversityMunicipal Clinical Hospital no. 40; Ural State Medical UniversityMunicipal Clinical Hospital no. 40; Ural State Medical UniversityAccording to the recommendations of the Surviving Sepsis Campaign (SSC), antibiotics should be administered within 1 hour after the onset of sepsis, and the centers for Medicare & Medicaid Services prescribe their administration within 3 hours.The objective of this publication is to analyze the literature data on the start time of ABT when a patient with sepsis is admitted to the ICU.Results. Currently, basing on literature analysis, it is impossible to conclude about advantages of administering an antibiotic within an hour after the patient with sepsis is admitted to a medical unit. In the vast majority of cases, an antibiotic should be administered up to three hours of the early IT complex (bundle). The change in the time algorithm for drug administration is due to the heterogeneity of the clinical situation, the lack of the unified "scenario" of interaction between the infection and host, and the need for more detail diagnostics.Conclusion. It is preferable to approach each case individually when deciding about the time to start ABT, considering the history, clinical and laboratory characteristics by the admission to the ICU. However, ABT should be started within 3 hours in any case.https://www.vair-journal.com/jour/article/view/467sepsisthe start time of antibacterial therapy
spellingShingle V. A. Rudnov
A. U. Lekmanov
V. A. Bagin
M. N. Аstafieva
When to start antibiotic therapy in patients with sepsis in the ICU?
Вестник анестезиологии и реаниматологии
sepsis
the start time of antibacterial therapy
title When to start antibiotic therapy in patients with sepsis in the ICU?
title_full When to start antibiotic therapy in patients with sepsis in the ICU?
title_fullStr When to start antibiotic therapy in patients with sepsis in the ICU?
title_full_unstemmed When to start antibiotic therapy in patients with sepsis in the ICU?
title_short When to start antibiotic therapy in patients with sepsis in the ICU?
title_sort when to start antibiotic therapy in patients with sepsis in the icu
topic sepsis
the start time of antibacterial therapy
url https://www.vair-journal.com/jour/article/view/467
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