Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China
Recently, there has been a continuous stream of reports on emerging tick-borne pathogens affecting humans. Qinghai Province, located in the northweastern region, is one of China’s major pastoral areas, providing a suitable environment for ticks' survival and transmitting tick-borne pathogens. H...
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Elsevier
2024-12-01
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| Series: | Biosafety and Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590053624001368 |
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| author | Chunfeng Luo Yonghong Song Luoyuan Xia Minxuan Liu Hao Feng Licheng Xiao Ming Xu Xiangyin Cai Jianye Cui Rong Xiang Jihu Yang Wei Kan Yanli Shen Yuanlian Ma Zhanhao Zeng Baohan Liu Yulian Tao Huimin Yu Yi Sun Xiaorun Wang Jiafu Jiang |
| author_facet | Chunfeng Luo Yonghong Song Luoyuan Xia Minxuan Liu Hao Feng Licheng Xiao Ming Xu Xiangyin Cai Jianye Cui Rong Xiang Jihu Yang Wei Kan Yanli Shen Yuanlian Ma Zhanhao Zeng Baohan Liu Yulian Tao Huimin Yu Yi Sun Xiaorun Wang Jiafu Jiang |
| author_sort | Chunfeng Luo |
| collection | DOAJ |
| description | Recently, there has been a continuous stream of reports on emerging tick-borne pathogens affecting humans. Qinghai Province, located in the northweastern region, is one of China’s major pastoral areas, providing a suitable environment for ticks' survival and transmitting tick-borne pathogens. Here, we collected 560 free-living and parasitic ticks from 11 locations in Qinghai Province using the flag-drag method or tweezers, identifying them as belonging to 4 species of ticks. The overall positivity rate for tick-borne pathogens was 51.61 %, comprising Rickettsia (34.64 %), Anaplasma (5.00 %), Ehrlichia (2.14 %), Borrelia burgdorferi sensu lato (BBSL) (7.50 %), Babesia (0.18 %), and Theileria (5.89 %). Sequencing revealed the presence of 7 species of Rickettsia, 4 species of Anaplasma, 2 species of Ehrlichia, 2 species of BBSL, 1 species of Babesia, and 3 species of Theileria. Among the ticks, 6.43 % were co-infected with 2 pathogens, while 0.36 % exhibited co-infection with 3 pathogens. Significant correlations (P < 0.05) were observed between the prevalence of tick-borne pathogens and factors including tick species, sex, developmental stages, parasitic status, and blood-feeding status. The results highlight the diverse distribution of tick-borne pathogens in Qinghai Province, posing a significant threat to both local animal husbandry and human health. It underscores the need to enhance systematic monitoring of tick-borne pathogens in the local population and livestock. |
| format | Article |
| id | doaj-art-3224b07904ed4b54aff901209b23ea2c |
| institution | DOAJ |
| issn | 2590-0536 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biosafety and Health |
| spelling | doaj-art-3224b07904ed4b54aff901209b23ea2c2025-08-20T02:57:35ZengElsevierBiosafety and Health2590-05362024-12-016636136810.1016/j.bsheal.2024.11.005Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern ChinaChunfeng Luo0Yonghong Song1Luoyuan Xia2Minxuan Liu3Hao Feng4Licheng Xiao5Ming Xu6Xiangyin Cai7Jianye Cui8Rong Xiang9Jihu Yang10Wei Kan11Yanli Shen12Yuanlian Ma13Zhanhao Zeng14Baohan Liu15Yulian Tao16Huimin Yu17Yi Sun18Xiaorun Wang19Jiafu Jiang20Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei 230032, China; State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, ChinaQinghai Provincial Animal Disease Prevention and Control Center, Xining 810000, ChinaState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, ChinaCollege of Veterinary Medicine, Gansu Agricultural University, Lanzhou 730000, China; State Key Laboratory Animal Disease Control and Prevention, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, ChinaState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, ChinaYushu City Animal Husbandry and Veterinary Station, Xining 815000, ChinaState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, ChinaHuzhu County Animal Husbandry and Veterinary Station, Xining 810500, ChinaLedu District Animal Husbandry and Veterinary Station, Xining 810700, ChinaState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei 230032, China; State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, ChinaQinghai Provincial Animal Disease Prevention and Control Center, Xining 810000, ChinaQinghai Provincial Animal Disease Prevention and Control Center, Xining 810000, ChinaHuzhu County Animal Husbandry and Veterinary Station, Xining 810500, ChinaQinghai Provincial Animal Disease Prevention and Control Center, Xining 810000, ChinaHuzhu County Animal Husbandry and Veterinary Station, Xining 810500, ChinaLedu District Animal Husbandry and Veterinary Station, Xining 810700, ChinaLedu District Animal Husbandry and Veterinary Station, Xining 810700, ChinaState Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, ChinaQinghai Provincial Animal Disease Prevention and Control Center, Xining 810000, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei 230032, China; State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, China; Corresponding author: State Key Laboratory of Pathogen and Biosecurity, Academy of Military Medical Sciences, Beijing 100071, China.Recently, there has been a continuous stream of reports on emerging tick-borne pathogens affecting humans. Qinghai Province, located in the northweastern region, is one of China’s major pastoral areas, providing a suitable environment for ticks' survival and transmitting tick-borne pathogens. Here, we collected 560 free-living and parasitic ticks from 11 locations in Qinghai Province using the flag-drag method or tweezers, identifying them as belonging to 4 species of ticks. The overall positivity rate for tick-borne pathogens was 51.61 %, comprising Rickettsia (34.64 %), Anaplasma (5.00 %), Ehrlichia (2.14 %), Borrelia burgdorferi sensu lato (BBSL) (7.50 %), Babesia (0.18 %), and Theileria (5.89 %). Sequencing revealed the presence of 7 species of Rickettsia, 4 species of Anaplasma, 2 species of Ehrlichia, 2 species of BBSL, 1 species of Babesia, and 3 species of Theileria. Among the ticks, 6.43 % were co-infected with 2 pathogens, while 0.36 % exhibited co-infection with 3 pathogens. Significant correlations (P < 0.05) were observed between the prevalence of tick-borne pathogens and factors including tick species, sex, developmental stages, parasitic status, and blood-feeding status. The results highlight the diverse distribution of tick-borne pathogens in Qinghai Province, posing a significant threat to both local animal husbandry and human health. It underscores the need to enhance systematic monitoring of tick-borne pathogens in the local population and livestock.http://www.sciencedirect.com/science/article/pii/S2590053624001368TickTick-borne pathogensCo-infectionDistribution of Qinghai Province |
| spellingShingle | Chunfeng Luo Yonghong Song Luoyuan Xia Minxuan Liu Hao Feng Licheng Xiao Ming Xu Xiangyin Cai Jianye Cui Rong Xiang Jihu Yang Wei Kan Yanli Shen Yuanlian Ma Zhanhao Zeng Baohan Liu Yulian Tao Huimin Yu Yi Sun Xiaorun Wang Jiafu Jiang Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China Biosafety and Health Tick Tick-borne pathogens Co-infection Distribution of Qinghai Province |
| title | Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China |
| title_full | Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China |
| title_fullStr | Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China |
| title_full_unstemmed | Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China |
| title_short | Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China |
| title_sort | molecular epidemiological study on tick borne pathogens in qinghai province northwestern china |
| topic | Tick Tick-borne pathogens Co-infection Distribution of Qinghai Province |
| url | http://www.sciencedirect.com/science/article/pii/S2590053624001368 |
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