Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation
Purpose. To evaluate the long-term anatomic and functional outcomes of autologous neurosensory retinal free flap transplantation (ART) for patients with refractory large macular hole (MH). Design. Retrospective interventional case series. Methods. We reviewed 9 patients who underwent ART for their r...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2022/1717366 |
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| author | Po-Yen Lee Yo-Chen Chang Pei-Kang Liu Tzu-En Kao Horng-Jiun Wu Kuo-Jen Chen Kwou-Yeung Wu Kai-Chun Cheng Wen-Chuan Wu |
| author_facet | Po-Yen Lee Yo-Chen Chang Pei-Kang Liu Tzu-En Kao Horng-Jiun Wu Kuo-Jen Chen Kwou-Yeung Wu Kai-Chun Cheng Wen-Chuan Wu |
| author_sort | Po-Yen Lee |
| collection | DOAJ |
| description | Purpose. To evaluate the long-term anatomic and functional outcomes of autologous neurosensory retinal free flap transplantation (ART) for patients with refractory large macular hole (MH). Design. Retrospective interventional case series. Methods. We reviewed 9 patients who underwent ART for their refractory large MH. In this extended follow-up study, postoperative assessment including spectral-domain optical coherence tomography and best-corrected visual acuity (BCVA) were recorded at 12, 15, 18, 21, and 24 months after surgery. Results. The macular hole of all patients appeared successfully closed during the whole follow-up period. The mean logMAR BCVA improved from 1.61 ± 0.44 (preoperative) to 0.72 ± 0.30 (12 months after surgery) (p<0.001). Thereafter, the mean BCVA remained stable at each follow-up. At the mean 16.0 ± 0.8 months postoperatively, inner retinal cystic changes were observed in 4 eyes (44.4%), but these did not significantly affect vision. Conclusion. ART is a good alternative technique for closing large refractory macular holes. Although inner retinal cystic changes were observed in 4 eyes (44.4%), this phenomenon did not significantly affect visual acuity. It provides long-term good anatomical and functional results, especially in cases where insufficient ILM or lens capsule are left. |
| format | Article |
| id | doaj-art-321e0df33d8e4723a3bb3b1224d92aeb |
| institution | Kabale University |
| issn | 2090-0058 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-321e0df33d8e4723a3bb3b1224d92aeb2025-08-20T03:55:06ZengWileyJournal of Ophthalmology2090-00582022-01-01202210.1155/2022/1717366Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap TransplantationPo-Yen Lee0Yo-Chen Chang1Pei-Kang Liu2Tzu-En Kao3Horng-Jiun Wu4Kuo-Jen Chen5Kwou-Yeung Wu6Kai-Chun Cheng7Wen-Chuan Wu8Department of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyPurpose. To evaluate the long-term anatomic and functional outcomes of autologous neurosensory retinal free flap transplantation (ART) for patients with refractory large macular hole (MH). Design. Retrospective interventional case series. Methods. We reviewed 9 patients who underwent ART for their refractory large MH. In this extended follow-up study, postoperative assessment including spectral-domain optical coherence tomography and best-corrected visual acuity (BCVA) were recorded at 12, 15, 18, 21, and 24 months after surgery. Results. The macular hole of all patients appeared successfully closed during the whole follow-up period. The mean logMAR BCVA improved from 1.61 ± 0.44 (preoperative) to 0.72 ± 0.30 (12 months after surgery) (p<0.001). Thereafter, the mean BCVA remained stable at each follow-up. At the mean 16.0 ± 0.8 months postoperatively, inner retinal cystic changes were observed in 4 eyes (44.4%), but these did not significantly affect vision. Conclusion. ART is a good alternative technique for closing large refractory macular holes. Although inner retinal cystic changes were observed in 4 eyes (44.4%), this phenomenon did not significantly affect visual acuity. It provides long-term good anatomical and functional results, especially in cases where insufficient ILM or lens capsule are left.http://dx.doi.org/10.1155/2022/1717366 |
| spellingShingle | Po-Yen Lee Yo-Chen Chang Pei-Kang Liu Tzu-En Kao Horng-Jiun Wu Kuo-Jen Chen Kwou-Yeung Wu Kai-Chun Cheng Wen-Chuan Wu Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation Journal of Ophthalmology |
| title | Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation |
| title_full | Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation |
| title_fullStr | Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation |
| title_full_unstemmed | Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation |
| title_short | Long-Term Follow-Up of Refractory Large Macular Hole with Autologous Neurosensory Retinal Free Flap Transplantation |
| title_sort | long term follow up of refractory large macular hole with autologous neurosensory retinal free flap transplantation |
| url | http://dx.doi.org/10.1155/2022/1717366 |
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