Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis
Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear. Objectives: This study aims to evaluate patient-reported outcomes (PROs) following chondroplasty in patients with larger chondral d...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-12-01
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| Series: | Journal of Cartilage & Joint Preservation |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S266725452400057X |
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| author | Yusuf Mufti Jared P. Sachs Andrew S. Bi Chloe Franzia John Ebersole Taylor Giordano Brian J. Cole |
| author_facet | Yusuf Mufti Jared P. Sachs Andrew S. Bi Chloe Franzia John Ebersole Taylor Giordano Brian J. Cole |
| author_sort | Yusuf Mufti |
| collection | DOAJ |
| description | Introduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear. Objectives: This study aims to evaluate patient-reported outcomes (PROs) following chondroplasty in patients with larger chondral defects (≥2 cm2) of the femur in the setting of osteoarthritis. Materials and methods: Retrospective review of patients who underwent chondroplasty of the femur. All patients had Kellgren-Lawrence (KL) grades of 2 or 3 and a minimum of 1-year postoperative follow-up. Chondral loss was estimated by arthroscopic measurements and by Magnetic Resonance Imaging (MRI). PROs included the International Knee Documentation Committee, Knee Injury and Osteoarthritis Outcome Score for Joint Replacement, and the Veterans Rand-12 Item. Statistical analysis was performed using paired t tests to compare baseline and follow-up data, as well as linear regressions to correlate lesion size with symptom improvement. Results: 39 patients with 20 KL grade 2 and 19 KL grade 3 knees were included. At both 1- and 2-year follow-ups, significant improvements were noted in International Knee Documentation Committee (34.9 ± 13.5 preoperative, 55.6 ± 18.8 at 2 years, P = .0025), Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (56.3 ± 14.7 preoperative, 64.5 ± 17.0 at 2 years, P = .0243), and Veterans Rand-12 Item Physical Component Scores (38.0 ± 12.7 preoperative, 43.8 ± 8.6 at 2 years, P = .0044). Four (10.3%) conversions to arthroplasty were noted at most recent follow-up. Conclusions: Articular cartilage debridement for large areas of cartilage loss of the femur in the setting of mild to moderate osteoarthritis results in significant improvements in physical function and knee-specific PROs at 1- and 2-year follow-ups. |
| format | Article |
| id | doaj-art-32179ea032894790b6694b219e26bb2b |
| institution | OA Journals |
| issn | 2667-2545 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Cartilage & Joint Preservation |
| spelling | doaj-art-32179ea032894790b6694b219e26bb2b2025-08-20T02:38:58ZengElsevierJournal of Cartilage & Joint Preservation2667-25452024-12-014410022110.1016/j.jcjp.2024.100221Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritisYusuf Mufti0Jared P. Sachs1Andrew S. Bi2Chloe Franzia3John Ebersole4Taylor Giordano5Brian J. Cole6Cartilage Restoration Center, Rush University Medical Center, Chicago, IL, USACartilage Restoration Center, Rush University Medical Center, Chicago, IL, USACartilage Restoration Center, Rush University Medical Center, Chicago, IL, USACartilage Restoration Center, Rush University Medical Center, Chicago, IL, USACartilage Restoration Center, Rush University Medical Center, Chicago, IL, USACartilage Restoration Center, Rush University Medical Center, Chicago, IL, USABrian J. Cole, Department of Orthopedic Surgery, Cartilage Restoration Center, Rush University Medical Center, 1611 W Harrison Street, Suite 300, Chicago, IL 60612.; Cartilage Restoration Center, Rush University Medical Center, Chicago, IL, USAIntroduction: Chondroplasty is a surgical option for chondral defects, but its effect on larger cartilage defects in the setting of knee osteoarthritis remains unclear. Objectives: This study aims to evaluate patient-reported outcomes (PROs) following chondroplasty in patients with larger chondral defects (≥2 cm2) of the femur in the setting of osteoarthritis. Materials and methods: Retrospective review of patients who underwent chondroplasty of the femur. All patients had Kellgren-Lawrence (KL) grades of 2 or 3 and a minimum of 1-year postoperative follow-up. Chondral loss was estimated by arthroscopic measurements and by Magnetic Resonance Imaging (MRI). PROs included the International Knee Documentation Committee, Knee Injury and Osteoarthritis Outcome Score for Joint Replacement, and the Veterans Rand-12 Item. Statistical analysis was performed using paired t tests to compare baseline and follow-up data, as well as linear regressions to correlate lesion size with symptom improvement. Results: 39 patients with 20 KL grade 2 and 19 KL grade 3 knees were included. At both 1- and 2-year follow-ups, significant improvements were noted in International Knee Documentation Committee (34.9 ± 13.5 preoperative, 55.6 ± 18.8 at 2 years, P = .0025), Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (56.3 ± 14.7 preoperative, 64.5 ± 17.0 at 2 years, P = .0243), and Veterans Rand-12 Item Physical Component Scores (38.0 ± 12.7 preoperative, 43.8 ± 8.6 at 2 years, P = .0044). Four (10.3%) conversions to arthroplasty were noted at most recent follow-up. Conclusions: Articular cartilage debridement for large areas of cartilage loss of the femur in the setting of mild to moderate osteoarthritis results in significant improvements in physical function and knee-specific PROs at 1- and 2-year follow-ups.http://www.sciencedirect.com/science/article/pii/S266725452400057XArticular cartilageCartilageChondroplastyDebridementOsteoarthritis |
| spellingShingle | Yusuf Mufti Jared P. Sachs Andrew S. Bi Chloe Franzia John Ebersole Taylor Giordano Brian J. Cole Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis Journal of Cartilage & Joint Preservation Articular cartilage Cartilage Chondroplasty Debridement Osteoarthritis |
| title | Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis |
| title_full | Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis |
| title_fullStr | Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis |
| title_full_unstemmed | Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis |
| title_short | Articular cartilage debridement results in short-term significant improvements in patient-reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis |
| title_sort | articular cartilage debridement results in short term significant improvements in patient reported outcomes for large areas of cartilage loss of the femur in the setting of mild to moderate knee osteoarthritis |
| topic | Articular cartilage Cartilage Chondroplasty Debridement Osteoarthritis |
| url | http://www.sciencedirect.com/science/article/pii/S266725452400057X |
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