Temporal Effects of Disease Signature Genes and Core Mechanisms in the Hyperacute Phase of Acute Ischemic Stroke: A Bioinformatics Analysis and Experimental Validation

Temporal Effects of Disease Signature Genes and Core Mechanisms in the Hyperacute Phase of Acute Ischemic Stroke: A Bioinformatics Analysis and Experimental Validation

Conclusion: This study systematically identifies hyperacute-phase-specific biomarkers in AIS and delineates their temporal regulatory logic. The time-course dynamics of neuronal apoptosis and inflammatory regulation in the hyperacute phase of AIS were monitored. The observed biphasic apoptotic patte...

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Main Authors: Peng-Li Ding, Kai-Xin Zhang, Fang Yao, Wen-Qiang Cui, Zhen-Ling Liu, Yi-Ran Wang, Xiang-Ying Wang, Wei Liu, Heng-Ye Zhao, Hong-Yun Wu, Ya-Han Wang, Xiang-Qing Xu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/mi/6808184
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