Effects of ATF2/TSC1 on epilepsy by modulating the microphages polarization of microglia

Abstract Epilepsy (EP) is a chronic nervous system disease characterized by recurrent attacks, and its causes are complicated. Inflammatory reaction mediated by microglia is an important factor in the progression of EP. Activating transcription factor 2 (ATF2) can be used as a transcription factor t...

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Bibliographic Details
Main Authors: Wenjiao Huang, Wenli Chen, Zhong Zhao, Lingchun Liu, Yuanyuan Zhao, Xinzhang Chen, Rong Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-04914-4
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