Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank Database

Aims: Recent evidence suggests that inflammation and immune dysregulation play a role in mental health disorders, including psychosis. Research has identified grey matter volume changes, however, the relationship between inflammation and functional connectivity remains underexplored. This study inve...

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Main Authors: Edward Palmer, Rachel Upthegrove, Jack Rogers
Format: Article
Language:English
Published: Cambridge University Press 2025-06-01
Series:BJPsych Open
Online Access:https://www.cambridge.org/core/product/identifier/S2056472425101026/type/journal_article
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author Edward Palmer
Rachel Upthegrove
Jack Rogers
author_facet Edward Palmer
Rachel Upthegrove
Jack Rogers
author_sort Edward Palmer
collection DOAJ
description Aims: Recent evidence suggests that inflammation and immune dysregulation play a role in mental health disorders, including psychosis. Research has identified grey matter volume changes, however, the relationship between inflammation and functional connectivity remains underexplored. This study investigates the impact of CRP levels on functional connectivity in psychosis.
format Article
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institution Kabale University
issn 2056-4724
language English
publishDate 2025-06-01
publisher Cambridge University Press
record_format Article
series BJPsych Open
spelling doaj-art-3213a8e009b54fc38f0ea144bd4012002025-08-20T03:32:22ZengCambridge University PressBJPsych Open2056-47242025-06-0111S12S1310.1192/bjo.2025.10102Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank DatabaseEdward Palmer0Rachel Upthegrove1Jack Rogers21University of Birmingham, Birmingham, United Kingdom 2Birmingham and Solihull Mental Health foundation Trust, Birmingham, United Kingdom3University of Oxford, Oxford, United Kingdom4University of Birmingham, Birmingham, United KingdomAims: Recent evidence suggests that inflammation and immune dysregulation play a role in mental health disorders, including psychosis. Research has identified grey matter volume changes, however, the relationship between inflammation and functional connectivity remains underexplored. This study investigates the impact of CRP levels on functional connectivity in psychosis.https://www.cambridge.org/core/product/identifier/S2056472425101026/type/journal_article
spellingShingle Edward Palmer
Rachel Upthegrove
Jack Rogers
Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank Database
BJPsych Open
title Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank Database
title_full Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank Database
title_fullStr Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank Database
title_full_unstemmed Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank Database
title_short Functional Connectivity Patterns Associated with Inflammation in Psychosis; Results From the UK Biobank Database
title_sort functional connectivity patterns associated with inflammation in psychosis results from the uk biobank database
url https://www.cambridge.org/core/product/identifier/S2056472425101026/type/journal_article
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AT jackrogers functionalconnectivitypatternsassociatedwithinflammationinpsychosisresultsfromtheukbiobankdatabase