Case report: post COVID-19 encephalopathy and oral cenesthopathy
Abstract Post-COVID-19 encephalopathy is a neurological complication characterized by cognitive impairment, memory loss, and other neuropsychiatric symptoms in COVID-19 survivors. Oral cenesthopathy, a rare somatic delusion characterized by unusual oral sensations without physical findings, is typic...
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| Format: | Article |
| Language: | English |
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BMC
2025-04-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-025-06789-1 |
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| author | Ju-I Wu Shwu-Hua Lee Pei-Jung Chen |
| author_facet | Ju-I Wu Shwu-Hua Lee Pei-Jung Chen |
| author_sort | Ju-I Wu |
| collection | DOAJ |
| description | Abstract Post-COVID-19 encephalopathy is a neurological complication characterized by cognitive impairment, memory loss, and other neuropsychiatric symptoms in COVID-19 survivors. Oral cenesthopathy, a rare somatic delusion characterized by unusual oral sensations without physical findings, is typically associated with affective disorders and schizophrenia. This case report describes a 73-year-old female who developed post-COVID-19 encephalopathy, presenting initially with cognitive decline, followed by major depression and oral cenesthopathy 16 months after the infection. Comprehensive investigations excluded autoimmune encephalitis, Creutzfeldt-Jakob disease, and other structural or vascular abnormalities. Treatment with Aripiprazole and Carbamazepine resulted in partial improvement, though symptom control was limited by medication side effects. This case represents a rare presentation of long COVID syndrome, highlighting the complex neuropsychiatric sequelae of COVID-19. Further research is needed to explore the pathophysiology, treatment strategies, and long-term impacts of such manifestations. |
| format | Article |
| id | doaj-art-320fca9f063b49a599e64a59eeee07f2 |
| institution | OA Journals |
| issn | 1471-244X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj-art-320fca9f063b49a599e64a59eeee07f22025-08-20T02:12:02ZengBMCBMC Psychiatry1471-244X2025-04-012511410.1186/s12888-025-06789-1Case report: post COVID-19 encephalopathy and oral cenesthopathyJu-I Wu0Shwu-Hua Lee1Pei-Jung Chen2Department of Psychiatry, Chang Gung Memorial HospitalDepartment of Psychiatry, Chang Gung Memorial HospitalDepartment of Psychiatry, Chang Gung Memorial HospitalAbstract Post-COVID-19 encephalopathy is a neurological complication characterized by cognitive impairment, memory loss, and other neuropsychiatric symptoms in COVID-19 survivors. Oral cenesthopathy, a rare somatic delusion characterized by unusual oral sensations without physical findings, is typically associated with affective disorders and schizophrenia. This case report describes a 73-year-old female who developed post-COVID-19 encephalopathy, presenting initially with cognitive decline, followed by major depression and oral cenesthopathy 16 months after the infection. Comprehensive investigations excluded autoimmune encephalitis, Creutzfeldt-Jakob disease, and other structural or vascular abnormalities. Treatment with Aripiprazole and Carbamazepine resulted in partial improvement, though symptom control was limited by medication side effects. This case represents a rare presentation of long COVID syndrome, highlighting the complex neuropsychiatric sequelae of COVID-19. Further research is needed to explore the pathophysiology, treatment strategies, and long-term impacts of such manifestations.https://doi.org/10.1186/s12888-025-06789-1Post COVID-19 encephalopathyLong COVID syndromeOral cenesthopathyDelusional disorder somatic typeCase report |
| spellingShingle | Ju-I Wu Shwu-Hua Lee Pei-Jung Chen Case report: post COVID-19 encephalopathy and oral cenesthopathy BMC Psychiatry Post COVID-19 encephalopathy Long COVID syndrome Oral cenesthopathy Delusional disorder somatic type Case report |
| title | Case report: post COVID-19 encephalopathy and oral cenesthopathy |
| title_full | Case report: post COVID-19 encephalopathy and oral cenesthopathy |
| title_fullStr | Case report: post COVID-19 encephalopathy and oral cenesthopathy |
| title_full_unstemmed | Case report: post COVID-19 encephalopathy and oral cenesthopathy |
| title_short | Case report: post COVID-19 encephalopathy and oral cenesthopathy |
| title_sort | case report post covid 19 encephalopathy and oral cenesthopathy |
| topic | Post COVID-19 encephalopathy Long COVID syndrome Oral cenesthopathy Delusional disorder somatic type Case report |
| url | https://doi.org/10.1186/s12888-025-06789-1 |
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