The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels

The aim of this study was to analyze the impact of a community-based exercise program in primary care on inflammatory biomarkers and hormone levels. The 1-year quasiexperimental study involved 13 women (mean age = 56.8 ± 11.4 years) and it was developed in two basic health care units in Rio Claro Ci...

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Main Authors: Camila Bosquiero Papini, Priscila M. Nakamura, Lucas P. Zorzetto, Janice L. Thompson, Anna C. Phillips, Eduardo Kokubun
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/185707
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author Camila Bosquiero Papini
Priscila M. Nakamura
Lucas P. Zorzetto
Janice L. Thompson
Anna C. Phillips
Eduardo Kokubun
author_facet Camila Bosquiero Papini
Priscila M. Nakamura
Lucas P. Zorzetto
Janice L. Thompson
Anna C. Phillips
Eduardo Kokubun
author_sort Camila Bosquiero Papini
collection DOAJ
description The aim of this study was to analyze the impact of a community-based exercise program in primary care on inflammatory biomarkers and hormone levels. The 1-year quasiexperimental study involved 13 women (mean age = 56.8 ± 11.4 years) and it was developed in two basic health care units in Rio Claro City, Brazil. The physical exercise intervention was comprised of two, 60-minute sessions/week. The inflammatory biomarkers were measured at baseline, 6 months, and 1 year. Repeated measures ANOVA analyses indicated that the intervention was effective in reducing CRP and TNFα after 1 year compared to baseline and 6 months (P<0.05). There were no changes in IL10, IL6, and insulin after 1 year. However, leptin significantly increased at 1 year (P=0.016). The major finding of this study is that a community-based exercise program can result in a decrease or maintenance of inflammatory biomarkers after 1 year, and thus has the potential to be a viable public health approach for chronic disease prevention.
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publishDate 2014-01-01
publisher Wiley
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series Mediators of Inflammation
spelling doaj-art-32045fff75924ef5be793320ef877bdb2025-08-20T02:07:40ZengWileyMediators of Inflammation0962-93511466-18612014-01-01201410.1155/2014/185707185707The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone LevelsCamila Bosquiero Papini0Priscila M. Nakamura1Lucas P. Zorzetto2Janice L. Thompson3Anna C. Phillips4Eduardo Kokubun5Department of Physical Education, São Paulo State University, Avenida 24-A, 1515 Bela Vista, 13506-900 Rio Claro, SP, BrazilDepartment of Physical Education, São Paulo State University, Avenida 24-A, 1515 Bela Vista, 13506-900 Rio Claro, SP, BrazilDepartment of Physical Education, São Paulo State University, Avenida 24-A, 1515 Bela Vista, 13506-900 Rio Claro, SP, BrazilSchool of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham, UKSchool of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham, UKDepartment of Physical Education, São Paulo State University, Avenida 24-A, 1515 Bela Vista, 13506-900 Rio Claro, SP, BrazilThe aim of this study was to analyze the impact of a community-based exercise program in primary care on inflammatory biomarkers and hormone levels. The 1-year quasiexperimental study involved 13 women (mean age = 56.8 ± 11.4 years) and it was developed in two basic health care units in Rio Claro City, Brazil. The physical exercise intervention was comprised of two, 60-minute sessions/week. The inflammatory biomarkers were measured at baseline, 6 months, and 1 year. Repeated measures ANOVA analyses indicated that the intervention was effective in reducing CRP and TNFα after 1 year compared to baseline and 6 months (P<0.05). There were no changes in IL10, IL6, and insulin after 1 year. However, leptin significantly increased at 1 year (P=0.016). The major finding of this study is that a community-based exercise program can result in a decrease or maintenance of inflammatory biomarkers after 1 year, and thus has the potential to be a viable public health approach for chronic disease prevention.http://dx.doi.org/10.1155/2014/185707
spellingShingle Camila Bosquiero Papini
Priscila M. Nakamura
Lucas P. Zorzetto
Janice L. Thompson
Anna C. Phillips
Eduardo Kokubun
The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels
Mediators of Inflammation
title The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels
title_full The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels
title_fullStr The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels
title_full_unstemmed The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels
title_short The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels
title_sort effect of a community based primary health care exercise program on inflammatory biomarkers and hormone levels
url http://dx.doi.org/10.1155/2014/185707
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