Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular Diseases
Cardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality rates globally, presenting a severe threat to human health and life. Acute myocardial infarction (AMI) is one of the most common and extremely severe disorders within CVDs, causing an estimated 17.5 million deaths...
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MDPI AG
2025-06-01
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| Series: | Biomolecules |
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| author | Ning Zhang Yusong Wang Fachuang Li Yuxin Zhu Zheng Fu Mengda Jia Xiaoran Zhan Wanqing Zhang |
| author_facet | Ning Zhang Yusong Wang Fachuang Li Yuxin Zhu Zheng Fu Mengda Jia Xiaoran Zhan Wanqing Zhang |
| author_sort | Ning Zhang |
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| description | Cardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality rates globally, presenting a severe threat to human health and life. Acute myocardial infarction (AMI) is one of the most common and extremely severe disorders within CVDs, causing an estimated 17.5 million deaths each year. Cardiac troponin I (cTnI) is considered a biomarker for myocardial infarction and a “gold standard” method for diagnosing AMI due to its high specificity and sensitivity. The ability to rapidly detect cTnI with high sensitivity is critical throughout the diagnosis and treatment process of AMI. It is a necessary precursor for doctors to quickly assess the disease and initiate subsequent therapies. This work comprehensively explores various techniques for the analysis and detection of cTnI. We systematically review current cutting-edge technologies used for cTnI detection. According to optical, electrical, and intelligent technology dimensions, this study meticulously classifies and elaborates on the research progress of related sensors. Based on current research findings and technological development trends, we further project the future research directions and application prospects of cTnI sensors. This is geared towards providing valuable references for the further development of this field. |
| format | Article |
| id | doaj-art-31f48cdde26d4c7fb3d4d9cf2c4738a6 |
| institution | OA Journals |
| issn | 2218-273X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | MDPI AG |
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| series | Biomolecules |
| spelling | doaj-art-31f48cdde26d4c7fb3d4d9cf2c4738a62025-08-20T02:24:23ZengMDPI AGBiomolecules2218-273X2025-06-0115685810.3390/biom15060858Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular DiseasesNing Zhang0Yusong Wang1Fachuang Li2Yuxin Zhu3Zheng Fu4Mengda Jia5Xiaoran Zhan6Wanqing Zhang7School of Materials Science and Engineering, Henan Institute of Technology, Xinxiang 453003, ChinaSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, ChinaSchool of Materials Science and Engineering, Henan Institute of Technology, Xinxiang 453003, ChinaSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, ChinaSchool of Materials Science and Engineering, Henan Institute of Technology, Xinxiang 453003, ChinaSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, ChinaSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, ChinaSchool of Chemistry and Chemical Engineering, Henan Institute of Science and Technology, Xinxiang 453003, ChinaCardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality rates globally, presenting a severe threat to human health and life. Acute myocardial infarction (AMI) is one of the most common and extremely severe disorders within CVDs, causing an estimated 17.5 million deaths each year. Cardiac troponin I (cTnI) is considered a biomarker for myocardial infarction and a “gold standard” method for diagnosing AMI due to its high specificity and sensitivity. The ability to rapidly detect cTnI with high sensitivity is critical throughout the diagnosis and treatment process of AMI. It is a necessary precursor for doctors to quickly assess the disease and initiate subsequent therapies. This work comprehensively explores various techniques for the analysis and detection of cTnI. We systematically review current cutting-edge technologies used for cTnI detection. According to optical, electrical, and intelligent technology dimensions, this study meticulously classifies and elaborates on the research progress of related sensors. Based on current research findings and technological development trends, we further project the future research directions and application prospects of cTnI sensors. This is geared towards providing valuable references for the further development of this field.https://www.mdpi.com/2218-273X/15/6/858cTnIsensoroptical technologyelectrical technologyintelligent technology |
| spellingShingle | Ning Zhang Yusong Wang Fachuang Li Yuxin Zhu Zheng Fu Mengda Jia Xiaoran Zhan Wanqing Zhang Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular Diseases Biomolecules cTnI sensor optical technology electrical technology intelligent technology |
| title | Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular Diseases |
| title_full | Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular Diseases |
| title_fullStr | Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular Diseases |
| title_full_unstemmed | Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular Diseases |
| title_short | Recent Advances in Monitoring Technologies for Cardiac Troponin I: A Pivotal Biomarker in Cardiovascular Diseases |
| title_sort | recent advances in monitoring technologies for cardiac troponin i a pivotal biomarker in cardiovascular diseases |
| topic | cTnI sensor optical technology electrical technology intelligent technology |
| url | https://www.mdpi.com/2218-273X/15/6/858 |
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