High sensitivity detection of Hepatitis B virus RNA based on 3D-DNA nanomachine and protein nanopore sensing
Abstract Serum Hepatitis B virus (HBV) RNA serves as a non-invasive biomarker for monitoring chronic hepatitis B and guiding treatment decisions. However, current diagnostic tests relying on Reverse Transcription Quantitative Polymerase Chain Reaction (RT-qPCR) require centralized facilities and ted...
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| Main Authors: | Shixin Yan, Chuipeng Kong, Jiazhe Cheng, Zhuoyun Tang, Ke Sun, Shanchuan Chen, Minghan Li, Chengyan Tao, Yue Li, Yanhua Zhao, Chuanmin Tao, Jia Geng, Feng Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-08-01
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| Series: | Molecular Biomedicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43556-025-00282-7 |
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