Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry Score
Context: Overnight oximetry is a screening test for pediatric obstructive sleep apnea (OSA). However, those who demonstrate normal/inconclusive test still require diagnostic polysomnography (PSG). Since PSG has a long waiting list, an adjunct simple test for the prioritization would be helpful. Aims...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-07-01
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| Series: | Pediatric Respirology and Critical Care Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/prcm.prcm_14_19 |
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| author | Supakanya Tansriratanawong Suchada Sritippayawan Montida Veeravigrom Jitladda Deerojanawong |
| author_facet | Supakanya Tansriratanawong Suchada Sritippayawan Montida Veeravigrom Jitladda Deerojanawong |
| author_sort | Supakanya Tansriratanawong |
| collection | DOAJ |
| description | Context:
Overnight oximetry is a screening test for pediatric obstructive sleep apnea (OSA). However, those who demonstrate normal/inconclusive test still require diagnostic polysomnography (PSG). Since PSG has a long waiting list, an adjunct simple test for the prioritization would be helpful.
Aims:
The aim of this study is to determine whether the OSA-18 quality of life (QoL) questionnaire could predict moderate-to-severe OSA in children with normal/inconclusive overnight oximetry.
Settings and Design:
The study involves a cross-sectional study at a university hospital.
Subjects and Methods:
Overnight PSG and QoL assessed by the Thai-Version OSA-18 were performed in snoring children with normal/inconclusive overnight oximetry.
Statistical Analysis:
Unpaired Student's t-test, Chi-square, and receiver operating characteristic curve analysis were used.
Results:
A total of 218 children (age 6.4 ± 2.5 years, 62% male) were studied. Sixty percent had moderate-to-severe OSA, while 40% had primary snoring/mild OSA. The mean total OSA-18 score was not different between the two groups. Subgroup analysis among those who never had medical treatment for OSA (n = 55) showed a higher total OSA-18 score in moderate-to-severe compared to primary snoring/mild OSA groups (80.5 ± 10.7 vs. 72.2 ± 14.4; P = 0.02). Total OSA-18 score >78 was the best cutoff value for predicting moderate-to-severe OSA (61.5% sensitivity, 80% specificity, 72.7% positive predictive value, and 69.7% negative predictive value). Combining this cutoff value with overweight/obesity did not improve its predictivity.
Conclusions:
We found the association between high total OSA-18 score and moderate-to-severe OSA in snoring children who had normal/inconclusive overnight oximetry and never had medical treatment for OSA. However, the best cutoff value of the score and other potential add-on parameters are still needed to be investigated. |
| format | Article |
| id | doaj-art-31dffdd28e844d2183d0fe6528beb4f7 |
| institution | DOAJ |
| issn | 2543-0343 2543-0351 |
| language | English |
| publishDate | 2019-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pediatric Respirology and Critical Care Medicine |
| spelling | doaj-art-31dffdd28e844d2183d0fe6528beb4f72025-08-20T03:13:51ZengWolters Kluwer Medknow PublicationsPediatric Respirology and Critical Care Medicine2543-03432543-03512019-07-0133606410.4103/prcm.prcm_14_19Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry ScoreSupakanya TansriratanawongSuchada SritippayawanMontida VeeravigromJitladda DeerojanawongContext: Overnight oximetry is a screening test for pediatric obstructive sleep apnea (OSA). However, those who demonstrate normal/inconclusive test still require diagnostic polysomnography (PSG). Since PSG has a long waiting list, an adjunct simple test for the prioritization would be helpful. Aims: The aim of this study is to determine whether the OSA-18 quality of life (QoL) questionnaire could predict moderate-to-severe OSA in children with normal/inconclusive overnight oximetry. Settings and Design: The study involves a cross-sectional study at a university hospital. Subjects and Methods: Overnight PSG and QoL assessed by the Thai-Version OSA-18 were performed in snoring children with normal/inconclusive overnight oximetry. Statistical Analysis: Unpaired Student's t-test, Chi-square, and receiver operating characteristic curve analysis were used. Results: A total of 218 children (age 6.4 ± 2.5 years, 62% male) were studied. Sixty percent had moderate-to-severe OSA, while 40% had primary snoring/mild OSA. The mean total OSA-18 score was not different between the two groups. Subgroup analysis among those who never had medical treatment for OSA (n = 55) showed a higher total OSA-18 score in moderate-to-severe compared to primary snoring/mild OSA groups (80.5 ± 10.7 vs. 72.2 ± 14.4; P = 0.02). Total OSA-18 score >78 was the best cutoff value for predicting moderate-to-severe OSA (61.5% sensitivity, 80% specificity, 72.7% positive predictive value, and 69.7% negative predictive value). Combining this cutoff value with overweight/obesity did not improve its predictivity. Conclusions: We found the association between high total OSA-18 score and moderate-to-severe OSA in snoring children who had normal/inconclusive overnight oximetry and never had medical treatment for OSA. However, the best cutoff value of the score and other potential add-on parameters are still needed to be investigated.https://journals.lww.com/10.4103/prcm.prcm_14_19childrenobstructive sleep apneaobstructive sleep apnea-18oximetry |
| spellingShingle | Supakanya Tansriratanawong Suchada Sritippayawan Montida Veeravigrom Jitladda Deerojanawong Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry Score Pediatric Respirology and Critical Care Medicine children obstructive sleep apnea obstructive sleep apnea-18 oximetry |
| title | Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry Score |
| title_full | Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry Score |
| title_fullStr | Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry Score |
| title_full_unstemmed | Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry Score |
| title_short | Usefulness of Obstructive Sleep Apnea-18 as a Predictor of Moderate-to-Severe Obstructive Sleep Apnea in Children Who Have Normal/Inconclusive McGill Oximetry Score |
| title_sort | usefulness of obstructive sleep apnea 18 as a predictor of moderate to severe obstructive sleep apnea in children who have normal inconclusive mcgill oximetry score |
| topic | children obstructive sleep apnea obstructive sleep apnea-18 oximetry |
| url | https://journals.lww.com/10.4103/prcm.prcm_14_19 |
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