Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children
The frequency of antinuclear antibodies (ANA) and rheumatoid factor (RF) was investigated in 118 apparently healthy children (56 male, 62 female). The mean age was 9.8 ± 2.3 years. Antinuclear antibodies (ANA) were detected by indirect immunofluorescence, using a Hep-2 cell substrate. Nephelometry...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
1999-01-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/3200 |
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| author | Özgür Kasapçopur Fatma Özbakır Nil Arısoy Hüseyin İngöl Hasan Yazıcı Huri Özdoğan |
| author_facet | Özgür Kasapçopur Fatma Özbakır Nil Arısoy Hüseyin İngöl Hasan Yazıcı Huri Özdoğan |
| author_sort | Özgür Kasapçopur |
| collection | DOAJ |
| description |
The frequency of antinuclear antibodies (ANA) and rheumatoid factor (RF) was investigated in 118 apparently healthy children (56 male, 62 female). The mean age was 9.8 ± 2.3 years. Antinuclear antibodies (ANA) were detected by indirect immunofluorescence, using a Hep-2 cell substrate. Nephelometry was used to quantify RF in 116 children. Five serum samples (4%, 3M, 2F) were ANA-positive in low titers and all had a speckled pattern. None of the ANA-positive children had other extractable antinuclear antibodies. Rheumatoid factor (RF) was over 25 lU/ml in four children (3%, 3F, 1M). None of these was positive for both antibodies.
Our results suggest a similar frequency of ANA in healthy Turkish children even with a Hep-2 cell substrate, when compared to results of other reports. On the other hand, RF was more frequent than in other reported series.
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| format | Article |
| id | doaj-art-31dceb2a3fa4461fa4be4307d8fd7786 |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 1999-01-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-31dceb2a3fa4461fa4be4307d8fd77862025-08-20T02:58:14ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64211999-01-0141110.24953/turkjpediatr.1999.3200Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish childrenÖzgür Kasapçopur0Fatma Özbakır1Nil Arısoy2Hüseyin İngöl3Hasan Yazıcı4Huri Özdoğan5İstanbul University Cerrahpaşa Faculty of Medicineİstanbul University Cerrahpaşa Faculty of Medicineİstanbul University Cerrahpaşa Faculty of MedicineAir Force Hospitalİstanbul University Cerrahpaşa Faculty of Medicineİstanbul University Cerrahpaşa Faculty of Medicine The frequency of antinuclear antibodies (ANA) and rheumatoid factor (RF) was investigated in 118 apparently healthy children (56 male, 62 female). The mean age was 9.8 ± 2.3 years. Antinuclear antibodies (ANA) were detected by indirect immunofluorescence, using a Hep-2 cell substrate. Nephelometry was used to quantify RF in 116 children. Five serum samples (4%, 3M, 2F) were ANA-positive in low titers and all had a speckled pattern. None of the ANA-positive children had other extractable antinuclear antibodies. Rheumatoid factor (RF) was over 25 lU/ml in four children (3%, 3F, 1M). None of these was positive for both antibodies. Our results suggest a similar frequency of ANA in healthy Turkish children even with a Hep-2 cell substrate, when compared to results of other reports. On the other hand, RF was more frequent than in other reported series. https://turkjpediatr.org/article/view/3200antinuclear antibodiesrheumatoid factorTurkish children |
| spellingShingle | Özgür Kasapçopur Fatma Özbakır Nil Arısoy Hüseyin İngöl Hasan Yazıcı Huri Özdoğan Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children The Turkish Journal of Pediatrics antinuclear antibodies rheumatoid factor Turkish children |
| title | Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children |
| title_full | Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children |
| title_fullStr | Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children |
| title_full_unstemmed | Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children |
| title_short | Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children |
| title_sort | frequency of antinuclear antibodies and rheumatoid factor in healthy turkish children |
| topic | antinuclear antibodies rheumatoid factor Turkish children |
| url | https://turkjpediatr.org/article/view/3200 |
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