Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review
Biosensors have the potential to revolutionize healthcare by providing rapid and accurate diagnosis of diseases. Biosensors are analytical devices that convert molecular recognition of a target analyte into a measurable signal. Older diagnostic techniques, such as immunoaffinity column assays, fluor...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2024-01-01
|
| Series: | Sensors International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666351123000517 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841560469884633088 |
|---|---|
| author | Ali Jawad Akki Pratheek Jain Ravindra Kulkarni Raghavendra Rao Badkillaya Raghavendra V. Kulkarni Farhan Zameer V Raghu Anjanapura Tejraj M. Aminabhavi |
| author_facet | Ali Jawad Akki Pratheek Jain Ravindra Kulkarni Raghavendra Rao Badkillaya Raghavendra V. Kulkarni Farhan Zameer V Raghu Anjanapura Tejraj M. Aminabhavi |
| author_sort | Ali Jawad Akki |
| collection | DOAJ |
| description | Biosensors have the potential to revolutionize healthcare by providing rapid and accurate diagnosis of diseases. Biosensors are analytical devices that convert molecular recognition of a target analyte into a measurable signal. Older diagnostic techniques, such as immunoaffinity column assays, fluorometric, and enzyme-linked immunosorbent assays, are laborious, require qualified personnel, and can be time consuming. In contrast, biosensors offer improved accuracy, sustainability, and rapidness due to their ability to detect specific biomarkers with high sensitivity and specificity. The review covers various bacterial cellulose (BC)-based biosensors, from SARS-CoV-2 detection to wearable health monitoring and interaction with human-computer interfaces. BC's integration into ionic thermoelectric hydrogels for wearable health monitoring shows its potential for real-time health tracking. Incorporating BC in biosensors for low-noise electrodes, and wearable sensors has been elaborated. The invention of a phage-immobilized BC biosensor for S. aureus detection is a significant contribution to the field, highlighting the biosafety and efficiency of BC in pathogen identification and demonstrating BC's versatility across multiple sensing platforms. Palladium nanoparticle-bacterial cellulose hybrid nanofibers show excellent electrocatalytic activity for dopamine detection, whereas Au-BC nanocomposite biosensors show efficacy in glucose detection, with potential therapeutic applications. The “lab-on-nanopaper” device, utilizing BC nanopaper, not only visually detects human serum albumin but also establishes itself as a new-generation optical biosensing platform with superiority over conventional substrates. This review contributes to the ongoing advancements in biosensor technology, highlighting the potential of BC as a versatile material for developing innovative biosensors. This is crucial for improving the accuracy, sensitivity, and efficiency of diagnostic tools in healthcare. |
| format | Article |
| id | doaj-art-31cd50f56f474c4ba080ce36f6329252 |
| institution | Kabale University |
| issn | 2666-3511 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Sensors International |
| spelling | doaj-art-31cd50f56f474c4ba080ce36f63292522025-01-04T04:57:07ZengKeAi Communications Co., Ltd.Sensors International2666-35112024-01-015100277Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A reviewAli Jawad Akki0Pratheek Jain1Ravindra Kulkarni2Raghavendra Rao Badkillaya3Raghavendra V. Kulkarni4Farhan Zameer5V Raghu Anjanapura6Tejraj M. Aminabhavi7Faculty of Science and Technology, BLDE (Deemed-to-be University), Vijayapura, 586 103, Karnataka, IndiaPathoGutOmic Laboratory, Alva's Traditional Medicine Archive (ATMA) Research Centre, Dakshina Kannada, 574 227, Karnataka, IndiaDepartment of Pharmaceutical Chemistry, BVDU's Poona College of Pharmacy, Erandawane, Pune, 411038, Maharashtra, IndiaPG Department of Biotechnology, Alva's College, Moodbidri, D.K, 574227, Karnataka, IndiaFaculty of Science and Technology, BLDE (Deemed-to-be University), Vijayapura, 586 103, Karnataka, India; Department of Pharmaceutics, BLDEA's SSM College of Pharmacy and Research Centre, Vijayapur, 586 103, Karnataka, IndiaPathoGutOmic Laboratory, Alva's Traditional Medicine Archive (ATMA) Research Centre, Dakshina Kannada, 574 227, Karnataka, India; Corresponding author.Faculty of Science and Technology, BLDE (Deemed-to-be University), Vijayapura, 586 103, Karnataka, India; Corresponding author.Center for Energy and Environment, School of Advanced Sciences, KLE Technological University, Hubballi, 580 031, IndiaBiosensors have the potential to revolutionize healthcare by providing rapid and accurate diagnosis of diseases. Biosensors are analytical devices that convert molecular recognition of a target analyte into a measurable signal. Older diagnostic techniques, such as immunoaffinity column assays, fluorometric, and enzyme-linked immunosorbent assays, are laborious, require qualified personnel, and can be time consuming. In contrast, biosensors offer improved accuracy, sustainability, and rapidness due to their ability to detect specific biomarkers with high sensitivity and specificity. The review covers various bacterial cellulose (BC)-based biosensors, from SARS-CoV-2 detection to wearable health monitoring and interaction with human-computer interfaces. BC's integration into ionic thermoelectric hydrogels for wearable health monitoring shows its potential for real-time health tracking. Incorporating BC in biosensors for low-noise electrodes, and wearable sensors has been elaborated. The invention of a phage-immobilized BC biosensor for S. aureus detection is a significant contribution to the field, highlighting the biosafety and efficiency of BC in pathogen identification and demonstrating BC's versatility across multiple sensing platforms. Palladium nanoparticle-bacterial cellulose hybrid nanofibers show excellent electrocatalytic activity for dopamine detection, whereas Au-BC nanocomposite biosensors show efficacy in glucose detection, with potential therapeutic applications. The “lab-on-nanopaper” device, utilizing BC nanopaper, not only visually detects human serum albumin but also establishes itself as a new-generation optical biosensing platform with superiority over conventional substrates. This review contributes to the ongoing advancements in biosensor technology, highlighting the potential of BC as a versatile material for developing innovative biosensors. This is crucial for improving the accuracy, sensitivity, and efficiency of diagnostic tools in healthcare.http://www.sciencedirect.com/science/article/pii/S2666351123000517Biosensors in healthcareRapid biomarker detectionPoint-of-care testingWearable biosensorsPersonalized medicineNanotechnology |
| spellingShingle | Ali Jawad Akki Pratheek Jain Ravindra Kulkarni Raghavendra Rao Badkillaya Raghavendra V. Kulkarni Farhan Zameer V Raghu Anjanapura Tejraj M. Aminabhavi Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review Sensors International Biosensors in healthcare Rapid biomarker detection Point-of-care testing Wearable biosensors Personalized medicine Nanotechnology |
| title | Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review |
| title_full | Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review |
| title_fullStr | Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review |
| title_full_unstemmed | Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review |
| title_short | Microbial biotechnology alchemy: Transforming bacterial cellulose into sensing disease- A review |
| title_sort | microbial biotechnology alchemy transforming bacterial cellulose into sensing disease a review |
| topic | Biosensors in healthcare Rapid biomarker detection Point-of-care testing Wearable biosensors Personalized medicine Nanotechnology |
| url | http://www.sciencedirect.com/science/article/pii/S2666351123000517 |
| work_keys_str_mv | AT alijawadakki microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview AT pratheekjain microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview AT ravindrakulkarni microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview AT raghavendraraobadkillaya microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview AT raghavendravkulkarni microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview AT farhanzameer microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview AT vraghuanjanapura microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview AT tejrajmaminabhavi microbialbiotechnologyalchemytransformingbacterialcelluloseintosensingdiseaseareview |