Single-Nucleus RNA Sequencing Reveals Muscle-Region-Specific Differences in Fibro-Adipogenic Progenitors Driving Intramuscular Fat Accumulation

Single-Nucleus RNA Sequencing Reveals Muscle-Region-Specific Differences in Fibro-Adipogenic Progenitors Driving Intramuscular Fat Accumulation

Background: Ectopic fat deposition refers to lipid accumulation that affects metabolic function and tissue characteristics. Japanese Black cattle are distinguished by their high intramuscular fat content, which contributes to their distinctive character. However, the genetic mechanisms underlying th...

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Bibliographic Details
Main Authors: Shuji Ueda, Chiaki Kitamura, Yuka Tateoka, Akinori Kanai, Yutaka Suzuki, Itsuko Fukuda, Yasuhito Shirai
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Metabolites
Subjects:
intramuscular fat
RNA sequencing
FAP
collagen
lipase
TGF-β
Online Access:https://www.mdpi.com/2218-1989/15/4/231
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