Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions
An efficient and facile synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives was developed through the isocyanide-based multicomponent reaction of isocyanides, gem-diactivated olefins, and cyclic imines such as dibenzoxazepine, dibenzothiazepine, and triazo...
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| Format: | Article |
| Language: | English |
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Beilstein-Institut
2024-11-01
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| Series: | Beilstein Journal of Organic Chemistry |
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| Online Access: | https://doi.org/10.3762/bjoc.20.241 |
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| author | Marzieh Norouzi Mohammad Taghi Nazeri Ahmad Shaabani Behrouz Notash |
| author_facet | Marzieh Norouzi Mohammad Taghi Nazeri Ahmad Shaabani Behrouz Notash |
| author_sort | Marzieh Norouzi |
| collection | DOAJ |
| description | An efficient and facile synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives was developed through the isocyanide-based multicomponent reaction of isocyanides, gem-diactivated olefins, and cyclic imines such as dibenzoxazepine, dibenzothiazepine, and triazolobenzodiazepine under solvent- and catalyst-free conditions. Purposefully, this approach produced various bioactive scaffolds using environmentally friendly, mild, and simple conditions. Due to their bioactive moieties, these compounds with exclusive fluorescence properties may attract great attention in biomedical applications, clinical diagnostics, and conjugate materials. |
| format | Article |
| id | doaj-art-31ab459933a44376bb32ec287fb8da2a |
| institution | Kabale University |
| issn | 1860-5397 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Beilstein-Institut |
| record_format | Article |
| series | Beilstein Journal of Organic Chemistry |
| spelling | doaj-art-31ab459933a44376bb32ec287fb8da2a2024-12-02T08:46:11ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972024-11-012012870288210.3762/bjoc.20.2411860-5397-20-241Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactionsMarzieh Norouzi0Mohammad Taghi Nazeri1Ahmad Shaabani2Behrouz Notash3Department of Organic Chemistry, Shahid Beheshti University, Daneshjou Boulevard, Tehran, 1983969411, Iran Department of Organic Chemistry, Shahid Beheshti University, Daneshjou Boulevard, Tehran, 1983969411, Iran Department of Organic Chemistry, Shahid Beheshti University, Daneshjou Boulevard, Tehran, 1983969411, Iran Department of Inorganic Chemistry, Shahid Beheshti University, Daneshjou Boulevard, Tehran, 1983969411, Iran An efficient and facile synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives was developed through the isocyanide-based multicomponent reaction of isocyanides, gem-diactivated olefins, and cyclic imines such as dibenzoxazepine, dibenzothiazepine, and triazolobenzodiazepine under solvent- and catalyst-free conditions. Purposefully, this approach produced various bioactive scaffolds using environmentally friendly, mild, and simple conditions. Due to their bioactive moieties, these compounds with exclusive fluorescence properties may attract great attention in biomedical applications, clinical diagnostics, and conjugate materials.https://doi.org/10.3762/bjoc.20.241cyclic iminesdibenzothiazepinedibenzoxazepineisocyanidesmulticomponent reactionspyrroletriazolobenzodiazepine |
| spellingShingle | Marzieh Norouzi Mohammad Taghi Nazeri Ahmad Shaabani Behrouz Notash Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions Beilstein Journal of Organic Chemistry cyclic imines dibenzothiazepine dibenzoxazepine isocyanides multicomponent reactions pyrrole triazolobenzodiazepine |
| title | Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions |
| title_full | Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions |
| title_fullStr | Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions |
| title_full_unstemmed | Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions |
| title_short | Synthesis of pyrrole-fused dibenzoxazepine/dibenzothiazepine/triazolobenzodiazepine derivatives via isocyanide-based multicomponent reactions |
| title_sort | synthesis of pyrrole fused dibenzoxazepine dibenzothiazepine triazolobenzodiazepine derivatives via isocyanide based multicomponent reactions |
| topic | cyclic imines dibenzothiazepine dibenzoxazepine isocyanides multicomponent reactions pyrrole triazolobenzodiazepine |
| url | https://doi.org/10.3762/bjoc.20.241 |
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