E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases

E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases

Numerous studies conducted in recent years indicate that mammalian E3 ubiquitin ligases serve as key regulators in the maintenance of cellular homeostasis by targeting the ubiquitination of substrate proteins and activating downstream signaling pathways. SYVN1, an E3 ubiquitin ligase, is characteriz...

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Bibliographic Details
Main Authors: Li Zhu, Yong-Ping Liu, Yuan-Wang, Bo-Xuan Sun, Yu-Ting Huang, Ji-Kai Zhao, Jian-Feng Liu, Li-Ming Yu, Hui-Shan Wang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Pharmacological Research
Subjects:
SYVN1
Cancer disease
E3 ubiquitin ligase
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825000283
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