Olfactory dysfunction and altered cortical excitability in the mouse model of Fragile X Syndrome

Olfactory dysfunction and altered cortical excitability in the mouse model of Fragile X Syndrome

Abstract Fragile X Syndrome (FXS) is the most common monogenetic cause of autism and inherited intellectual disability. A key feature of FXS symptomatology is altered sensory processing greatly affecting FXS individual’s life quality. Here, we use a combination of behavioral tests and slice physiolo...

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Bibliographic Details
Main Authors: Felipe Arancibia, Marcelo Rojas, Diego Becerra, Rocío Fuenzalida, Christian Cea-Del Rio, Jorge Mpodozis, Magdalena Sanhueza, Alexia Nunez-Parra
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Biological Research
Subjects:
Sensory processing
Autism spectrum disorder (ASD)
Fmr1 KO
Perceptual stability
Olfactory discrimination
Online Access:https://doi.org/10.1186/s40659-024-00582-2
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