Unveiling the processing mechanism of Hezi-decoction-processed Tiebangchui: a synthesis approach using UPLC-Q-TOF-MS-based metabolomics and DESI-MSI

Unveiling the processing mechanism of Hezi-decoction-processed Tiebangchui: a synthesis approach using UPLC-Q-TOF-MS-based metabolomics and DESI-MSI

IntroductionTiebangchui (TBC, Tibetan name: བང་ང་ནག་པ།), the dried tuberous root of Aconitum pendulum Busch. and Aconitum flavaum Hand.-Mazz., is a prevalent used Tibetan medicine, recognized for its significant therapeutic effects despite its high toxicity. It is commonly employed in treating the d...

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Bibliographic Details
Main Authors: Zhen Zhou, Hui-Min Gao, Zhao-Qin Pei, Meng-Xiang Sha, Cong-Ying Li, Yi Zhang, Jin-Song Su, Yue Liu, Xian-Li Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
Tiebangchui
UPLC-Q-ToF-MS
Hezi-decoction-processed
toxicity attenuation
DESI-MSI
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1534748/full
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