Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis

Purpose: Achieving biological fixation of the often loosened tibia is increasingly important for total knee arthroplasty (TKA), with one key factor being the bone density of the proximal tibia. This study examined whether hip bone mineral density (BMD), the most common diagnostic tool for osteoporos...

Full description

Saved in:
Bibliographic Details
Main Authors: Junya Itou, Ayano Kuwasawa, Kotaro Nihei, Ken Okazaki
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Joint Surgery and Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2949705125000131
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849222498860662784
author Junya Itou
Ayano Kuwasawa
Kotaro Nihei
Ken Okazaki
author_facet Junya Itou
Ayano Kuwasawa
Kotaro Nihei
Ken Okazaki
author_sort Junya Itou
collection DOAJ
description Purpose: Achieving biological fixation of the often loosened tibia is increasingly important for total knee arthroplasty (TKA), with one key factor being the bone density of the proximal tibia. This study examined whether hip bone mineral density (BMD), the most common diagnostic tool for osteoporosis, can estimate tibial BMD in both sexes. Methods: This retrospective study included patients who underwent primary TKA with hip and tibial BMD measurement. Tibial BMD was measured 10 ​mm distal to the lateral tibial articular surface, separately for the medial (BMDm) and lateral (BMDl) sides. Additionally, the association between BMD and lower limb alignment was evaluated. Results: In total, 1012 knees were included (79.3% in women). The mean patient age at surgery was 73.3 ​± ​7.5 years. The mean total hip BMD for women and men was 0.79 ​± ​0.13 ​g/cm2 and 0.95 ​± ​0.16 ​g/cm2, respectively. The mean BMDm and BMDl was, respectively, 0.75 ​± ​0.16 ​g/cm2 and 0.63 ​± ​0.13 ​g/cm2 in women and 0.92 ​± ​0.18 ​g/cm2 and 0.89 ​± ​0.18 ​g/cm2 in men. Both BMDm and BMDl showed a moderate correlation with hip BMD (r ​= ​0.67 and 0.66, respectively) in men. In women, BMDm showed a weak correlation (r ​= ​0.47). Regarding lower limb alignment, BMDm was significantly higher in varus alignment than in neutral or valgus alignment. BMDl did not change with lower limb alignment. Conclusions: BMDm and BMDl were moderately correlated with hip BMD in men, while BMDm showed a low correlation in women.
format Article
id doaj-art-31991c877a2f404ca8d59b805e69d54a
institution Kabale University
issn 2949-7051
language English
publishDate 2025-09-01
publisher Elsevier
record_format Article
series Journal of Joint Surgery and Research
spelling doaj-art-31991c877a2f404ca8d59b805e69d54a2025-08-26T04:14:49ZengElsevierJournal of Joint Surgery and Research2949-70512025-09-013312112710.1016/j.jjoisr.2025.06.001Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritisJunya Itou0Ayano Kuwasawa1Kotaro Nihei2Ken Okazaki3Department of Orthopaedic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, Japan; Department of Orthopaedic Surgery, Saitama Cooperative Hospital, 1317 Kizoro, Kawaguchi, Saitama 333-0831 JapanDepartment of Orthopaedic Surgery, Saitama Cooperative Hospital, 1317 Kizoro, Kawaguchi, Saitama 333-0831 Japan; Corresponding author. Department of Orthopaedic Surgery, Saitama Cooperative Hospital, 1317 Kizoro, Kawaguchi, Saitama 333-0831, Japan.Department of Orthopaedic Surgery, Saitama Cooperative Hospital, 1317 Kizoro, Kawaguchi, Saitama 333-0831 JapanDepartment of Orthopaedic Surgery, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku, Tokyo 162-8666, JapanPurpose: Achieving biological fixation of the often loosened tibia is increasingly important for total knee arthroplasty (TKA), with one key factor being the bone density of the proximal tibia. This study examined whether hip bone mineral density (BMD), the most common diagnostic tool for osteoporosis, can estimate tibial BMD in both sexes. Methods: This retrospective study included patients who underwent primary TKA with hip and tibial BMD measurement. Tibial BMD was measured 10 ​mm distal to the lateral tibial articular surface, separately for the medial (BMDm) and lateral (BMDl) sides. Additionally, the association between BMD and lower limb alignment was evaluated. Results: In total, 1012 knees were included (79.3% in women). The mean patient age at surgery was 73.3 ​± ​7.5 years. The mean total hip BMD for women and men was 0.79 ​± ​0.13 ​g/cm2 and 0.95 ​± ​0.16 ​g/cm2, respectively. The mean BMDm and BMDl was, respectively, 0.75 ​± ​0.16 ​g/cm2 and 0.63 ​± ​0.13 ​g/cm2 in women and 0.92 ​± ​0.18 ​g/cm2 and 0.89 ​± ​0.18 ​g/cm2 in men. Both BMDm and BMDl showed a moderate correlation with hip BMD (r ​= ​0.67 and 0.66, respectively) in men. In women, BMDm showed a weak correlation (r ​= ​0.47). Regarding lower limb alignment, BMDm was significantly higher in varus alignment than in neutral or valgus alignment. BMDl did not change with lower limb alignment. Conclusions: BMDm and BMDl were moderately correlated with hip BMD in men, while BMDm showed a low correlation in women.http://www.sciencedirect.com/science/article/pii/S2949705125000131Total knee arthroplastyBone mineral densityCementlessAlignment
spellingShingle Junya Itou
Ayano Kuwasawa
Kotaro Nihei
Ken Okazaki
Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis
Journal of Joint Surgery and Research
Total knee arthroplasty
Bone mineral density
Cementless
Alignment
title Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis
title_full Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis
title_fullStr Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis
title_full_unstemmed Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis
title_short Proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis
title_sort proximal tibia bone mineral density correlates more closely with hip density in men with knee osteoarthritis
topic Total knee arthroplasty
Bone mineral density
Cementless
Alignment
url http://www.sciencedirect.com/science/article/pii/S2949705125000131
work_keys_str_mv AT junyaitou proximaltibiabonemineraldensitycorrelatesmorecloselywithhipdensityinmenwithkneeosteoarthritis
AT ayanokuwasawa proximaltibiabonemineraldensitycorrelatesmorecloselywithhipdensityinmenwithkneeosteoarthritis
AT kotaronihei proximaltibiabonemineraldensitycorrelatesmorecloselywithhipdensityinmenwithkneeosteoarthritis
AT kenokazaki proximaltibiabonemineraldensitycorrelatesmorecloselywithhipdensityinmenwithkneeosteoarthritis