ERK1/2 signalling dynamics promote neural differentiation by regulating chromatin accessibility and the polycomb repressive complex.
Fibroblast growth factor (FGF) is a neural inducer in many vertebrate embryos, but how it regulates chromatin organization to coordinate the activation of neural genes is unclear. Moreover, for differentiation to progress, FGF signalling must decline. Why these signalling dynamics are required has n...
Saved in:
| Main Authors: | Claudia I Semprich, Lindsay Davidson, Adriana Amorim Torres, Harshil Patel, James Briscoe, Vicki Metzis, Kate G Storey |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-12-01
|
| Series: | PLoS Biology |
| Online Access: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3000221&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Chromatin sampling--an emerging perspective on targeting polycomb repressor proteins.
by: Robert J Klose, et al.
Published: (2013-01-01) -
Polycomb repressive complex 2 controls the embryo-to-seedling phase transition.
by: Daniel Bouyer, et al.
Published: (2011-03-01) -
A polycomb group protein is retained at specific sites on chromatin in mitosis.
by: Nicole E Follmer, et al.
Published: (2012-01-01) -
Accelerated epigenetic aging in Huntington’s disease involves polycomb repressive complex 1
by: Baptiste Brulé, et al.
Published: (2025-02-01) -
Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.
by: Shih Chieh Liang, et al.
Published: (2015-12-01)