Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial Resuscitation
Background: Trauma-induced coagulopathy (TIC) denotes abnormal blood clotting that occurs as a result of a physical injury. During the initial stages of trauma-induced coagulopathy development, there is usually a condition of reduced blood clotting ability, leading to bleeding. Objectives: This stu...
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| Format: | Article |
| Language: | English |
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South Valley University, Faculty of Medicine
2024-07-01
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| Series: | SVU - International Journal of Medical Sciences |
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| Online Access: | https://svuijm.journals.ekb.eg/article_382103.html |
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| author | Yahya Abdel Tawab Mohammed Meky* |
| author_facet | Yahya Abdel Tawab Mohammed Meky* |
| author_sort | Yahya Abdel Tawab Mohammed Meky* |
| collection | DOAJ |
| description | Background: Trauma-induced coagulopathy (TIC) denotes abnormal blood clotting that occurs as a result of a physical injury. During the initial stages of trauma-induced coagulopathy development, there is usually a condition of reduced blood clotting ability, leading to bleeding.
Objectives: This study aimed to ascertain the difference between using albumin and ringer lactate in resuscitation of traumatized patients and their impact on blood coagulation.
Patients and methods: This prospective comparative study was carried out on 80 patients aged above 18 years old, both sexes, trauma induced coagulopathy clinical score over 10. Patients were divided into two equal groups: Group A: received ringer lactate, and group B: received albumin.
Results: Coagulation test at day 1, 2 and 3 of initial resuscitation were insignificantly different between both groups. Regarding coagulation tests in Group A, B were insignificantly different amongst coagulation tests at days 1 and 3 of initial resuscitation. However, there was improvement of the coagulation test results during day 3 of initial resuscitation. Changes in platelet count and hemoglobin at different intervals of time were insignificantly different between both groups.
Conclusion: The effect of administration of albumin solution with Ringer’s lactate on blood coagulation in TIC during initial resuscitation showed no difference as regard effect on coagulation profile between two groups, but patients received albumin showed better improvement in resuscitation parameters on the second day in comparison to the patients received Ringer’s lactate. |
| format | Article |
| id | doaj-art-3190250dae4041d99d0728e3958190ec |
| institution | Kabale University |
| issn | 2735-427X 2636-3402 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | South Valley University, Faculty of Medicine |
| record_format | Article |
| series | SVU - International Journal of Medical Sciences |
| spelling | doaj-art-3190250dae4041d99d0728e3958190ec2025-01-23T10:02:04ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022024-07-0172508516https://doi.org/10.21608/svuijm.2024.306891.1941Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial ResuscitationYahya Abdel Tawab Mohammed Meky*0Intensive Care Department, Faculty of Medicine, Military Medical Academy, Armed Forces College of Medicine, EgyptBackground: Trauma-induced coagulopathy (TIC) denotes abnormal blood clotting that occurs as a result of a physical injury. During the initial stages of trauma-induced coagulopathy development, there is usually a condition of reduced blood clotting ability, leading to bleeding. Objectives: This study aimed to ascertain the difference between using albumin and ringer lactate in resuscitation of traumatized patients and their impact on blood coagulation. Patients and methods: This prospective comparative study was carried out on 80 patients aged above 18 years old, both sexes, trauma induced coagulopathy clinical score over 10. Patients were divided into two equal groups: Group A: received ringer lactate, and group B: received albumin. Results: Coagulation test at day 1, 2 and 3 of initial resuscitation were insignificantly different between both groups. Regarding coagulation tests in Group A, B were insignificantly different amongst coagulation tests at days 1 and 3 of initial resuscitation. However, there was improvement of the coagulation test results during day 3 of initial resuscitation. Changes in platelet count and hemoglobin at different intervals of time were insignificantly different between both groups. Conclusion: The effect of administration of albumin solution with Ringer’s lactate on blood coagulation in TIC during initial resuscitation showed no difference as regard effect on coagulation profile between two groups, but patients received albumin showed better improvement in resuscitation parameters on the second day in comparison to the patients received Ringer’s lactate.https://svuijm.journals.ekb.eg/article_382103.htmltrauma-induced coagulopathy initial resuscitationalbumin ringer lactate coagulation |
| spellingShingle | Yahya Abdel Tawab Mohammed Meky* Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial Resuscitation SVU - International Journal of Medical Sciences trauma-induced coagulopathy initial resuscitation albumin ringer lactate coagulation |
| title | Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial Resuscitation |
| title_full | Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial Resuscitation |
| title_fullStr | Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial Resuscitation |
| title_full_unstemmed | Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial Resuscitation |
| title_short | Comparing the Effect of Albumin 5% versus Ringer Lactate on Blood Coagulation in Trauma-Induced Coagulopathy during Initial Resuscitation |
| title_sort | comparing the effect of albumin 5 versus ringer lactate on blood coagulation in trauma induced coagulopathy during initial resuscitation |
| topic | trauma-induced coagulopathy initial resuscitation albumin ringer lactate coagulation |
| url | https://svuijm.journals.ekb.eg/article_382103.html |
| work_keys_str_mv | AT yahyaabdeltawabmohammedmeky comparingtheeffectofalbumin5versusringerlactateonbloodcoagulationintraumainducedcoagulopathyduringinitialresuscitation |