Rare infantile sepsis and meningitis caused by Pasteurella multocida: A case report

This case report highlights a rare instance of Pasteurella multocida meningitis in a 2-month-old infant, complicated by subdural empyema. The pathogen was identified using next-generation sequencing (NGS), despite negative bacterial cultures, underscoring the diagnostic challenges. The strain was pr...

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Bibliographic Details
Main Authors: Ming-ming Ni, Wen-xin Lin, Yang Li, Jin-chun Qiu, Chun-feng Wu
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Infection and Public Health
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Online Access:http://www.sciencedirect.com/science/article/pii/S1876034125001716
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Summary:This case report highlights a rare instance of Pasteurella multocida meningitis in a 2-month-old infant, complicated by subdural empyema. The pathogen was identified using next-generation sequencing (NGS), despite negative bacterial cultures, underscoring the diagnostic challenges. The strain was predicted to be resistant to meropenem and ampicillin, necessitating a tailored treatment approach. The strain was likely transmitted through a neighbor's dog, emphasizing the complexity of P. multocida transmission. This case underscores the importance of advanced diagnostic techniques and personalized therapy for managing rare, antibiotic-resistant infections.
ISSN:1876-0341