Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life?
According to the ejection fraction, patients with heart failure may be divided into two different groups: heart failure with preserved or reduced ejection fraction. In recent years, accumulating studies showed that increased mortality and morbidity rates of these two groups are nearly equal. More im...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2013/130724 |
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| _version_ | 1832553934794784768 |
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| author | Jia Li Peter Moritz Becher Stefan Blankenberg Dirk Westermann |
| author_facet | Jia Li Peter Moritz Becher Stefan Blankenberg Dirk Westermann |
| author_sort | Jia Li |
| collection | DOAJ |
| description | According to the ejection fraction, patients with heart failure may be divided into two different groups: heart failure with preserved or reduced ejection fraction. In recent years, accumulating studies showed that increased mortality and morbidity rates of these two groups are nearly equal. More importantly, despite decline in mortality after treatment in regard to current guideline in patients with heart failure with reduced ejection fraction, there are still no trials resulting in improved outcome in patients with heart failure with preserved ejection fraction so far. Thus, novel pathophysiological mechanisms are under development, and other new viewpoints, such as multiple comorbidities resulting in increased non-cardiac deaths in patients with heart failure and preserved ejection fraction, were presented recently. In this review, we will focus on the tested as well as the promising therapeutic options that are currently studied in patients with heart failure with preserved ejection fraction, along with a brief discussion of pathophysiological mechanisms and diagnostic options that are helpful to increase our understanding of novel therapeutic strategies. |
| format | Article |
| id | doaj-art-317b791511e04905ab246b98326ef367 |
| institution | Kabale University |
| issn | 2090-8016 2090-0597 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-317b791511e04905ab246b98326ef3672025-02-03T05:52:41ZengWileyCardiology Research and Practice2090-80162090-05972013-01-01201310.1155/2013/130724130724Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life?Jia Li0Peter Moritz Becher1Stefan Blankenberg2Dirk Westermann3Department of General and Interventional Cardiology, University Heart Center Hamburg Eppendorf, Martinistraße 52, 20246 Hamburg, GermanyDepartment of General and Interventional Cardiology, University Heart Center Hamburg Eppendorf, Martinistraße 52, 20246 Hamburg, GermanyDepartment of General and Interventional Cardiology, University Heart Center Hamburg Eppendorf, Martinistraße 52, 20246 Hamburg, GermanyDepartment of General and Interventional Cardiology, University Heart Center Hamburg Eppendorf, Martinistraße 52, 20246 Hamburg, GermanyAccording to the ejection fraction, patients with heart failure may be divided into two different groups: heart failure with preserved or reduced ejection fraction. In recent years, accumulating studies showed that increased mortality and morbidity rates of these two groups are nearly equal. More importantly, despite decline in mortality after treatment in regard to current guideline in patients with heart failure with reduced ejection fraction, there are still no trials resulting in improved outcome in patients with heart failure with preserved ejection fraction so far. Thus, novel pathophysiological mechanisms are under development, and other new viewpoints, such as multiple comorbidities resulting in increased non-cardiac deaths in patients with heart failure and preserved ejection fraction, were presented recently. In this review, we will focus on the tested as well as the promising therapeutic options that are currently studied in patients with heart failure with preserved ejection fraction, along with a brief discussion of pathophysiological mechanisms and diagnostic options that are helpful to increase our understanding of novel therapeutic strategies.http://dx.doi.org/10.1155/2013/130724 |
| spellingShingle | Jia Li Peter Moritz Becher Stefan Blankenberg Dirk Westermann Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life? Cardiology Research and Practice |
| title | Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life? |
| title_full | Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life? |
| title_fullStr | Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life? |
| title_full_unstemmed | Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life? |
| title_short | Current Treatment of Heart Failure with Preserved Ejection Fraction: Should We Add Life to the Remaining Years or Add Years to the Remaining Life? |
| title_sort | current treatment of heart failure with preserved ejection fraction should we add life to the remaining years or add years to the remaining life |
| url | http://dx.doi.org/10.1155/2013/130724 |
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