Сirculating osteonectin as a prognostic biological marker in patients with ischemic chronic heart failure
Aim: To evaluate the prognostic value of circulating osteonectin for cumulative survival in patients with ischemic chronic heart failure (CHF). Methods: A total of 154 patients with ischemic symptomatic moderate-to-severe CHF were enrolled in the study. Observation period was up to 3 years. ELISA...
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| Format: | Article |
| Language: | English |
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Zaporizhzhia State Medical and Pharmaceutical University
2014-08-01
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| Series: | Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki |
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| Online Access: | http://pharmed.zsmu.edu.ua/article/view/26166/23624 |
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| Summary: | Aim: To evaluate the prognostic value of circulating osteonectin for cumulative survival in patients with ischemic chronic heart failure (CHF).
Methods: A total of 154 patients with ischemic symptomatic moderate-to-severe CHF were enrolled in the study. Observation period was up to 3 years. ELISA methods for measurements of circulating level of osteonectin were used. Concentrations of osteonectin for cumulative survival cases due to advanced CHF were tested. Additionally, all-cause mortality, and CHF-related death were examined.
Conclusion: Increased circulating osteonectin associates with increased 3-year CHF-related death, and risk for hospitalization due to CHF. |
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| ISSN: | 2306-8094 2409-2932 |