Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experiment
Introduction Pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV acquisition, but coverage remains low in high prevalence settings. Initiating and continuing PrEP via online pharmacies is a promising strategy to expand PrEP uptake but little is known about user preferences for this...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2023-04-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/4/e069195.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850062998604873728 |
|---|---|
| author | Melissa Latigo Mugambi Katrina F Ortblad Kenneth Ngure Catherine Kiptinness Fern Terris-Prestholt Monisha Sharma Andy Stergachis Yilin Chen Enrique M Saldarriaga Michalina A Montano Nicholas Thuo Maeve Rafferty |
| author_facet | Melissa Latigo Mugambi Katrina F Ortblad Kenneth Ngure Catherine Kiptinness Fern Terris-Prestholt Monisha Sharma Andy Stergachis Yilin Chen Enrique M Saldarriaga Michalina A Montano Nicholas Thuo Maeve Rafferty |
| author_sort | Melissa Latigo Mugambi |
| collection | DOAJ |
| description | Introduction Pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV acquisition, but coverage remains low in high prevalence settings. Initiating and continuing PrEP via online pharmacies is a promising strategy to expand PrEP uptake but little is known about user preferences for this strategy. We describe methods for a discrete choice experiment (DCE) to assess preferences for PrEP delivery from an online pharmacy.Methods and analysis This cross-sectional study is conducted in Nairobi, Kenya, in partnership with MYDAWA, a private online pharmacy retailer with a planned sample size of >400 participants. Eligibility criteria are: ≥18 years, not known HIV-positive and interested in PrEP. Initial DCE attributes and levels were developed via literature review and stakeholder meetings. We conducted cognitive interviews to assess participant understanding of the DCE survey and refined the design. The final DCE used a D-efficient design and contained four attributes: PrEP eligibility assessment, HIV test type, clinical consultation type and user support options. Participants are presented with eight scenarios consisting of two hypothetical PrEP delivery services. The survey was piloted among 20 participants before being advertised on the MYDAWA website on pages displaying products indicating HIV risk (eg, HIV self-test kits). Interested participants call a study number and those screened eligible meet a research assistant in a convenient location to complete the survey. The DCE will be analysed using a conditional logit model to assess average preferences and mixed logit and latent class models to evaluate preference heterogeneity among subgroups.Ethics and dissemination This study was approved by the University of Washington Human Research Ethics Committee (STUDY00014011), the Kenya Medical Research Institute, Nairobi County (EOP/NMS/HS/128) and the Scientific and Ethics Review Unit in Kenya (KEMRI/RES/7/3/1). Participation in the DCE is voluntary and subject to completion of an electronic informed consent. Findings will be shared at international conferences and peer-reviewed publications, and via engagement meetings with stakeholders. |
| format | Article |
| id | doaj-art-3174007fdf6e4a32929c8a6ba3ef5c09 |
| institution | DOAJ |
| issn | 2044-6055 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-3174007fdf6e4a32929c8a6ba3ef5c092025-08-20T02:49:47ZengBMJ Publishing GroupBMJ Open2044-60552023-04-0113410.1136/bmjopen-2022-069195Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experimentMelissa Latigo Mugambi0Katrina F Ortblad1Kenneth Ngure2Catherine Kiptinness3Fern Terris-Prestholt4Monisha Sharma5Andy Stergachis6Yilin Chen7Enrique M Saldarriaga8Michalina A Montano9Nicholas Thuo10Maeve Rafferty11Department of Global Health, University of Washington, Seattle, Washington, USAPublic Health Science Division, Fred Hutchinson Cancer Center, Seattle, Washington, USACommunity Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, KenyaCenter for Clinical Research, Kenya Medical Research Institute, Nairobi, KenyaWarwick Medical School, University of Warwick, Coventry, UKDepartment of Global Health, University of Washington, Seattle, Washington, USADepartment of Pharmacy, University of Washington School of Public Health, Seattle, Washington, USAThe Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, ChinaUniversity of Washington, Seattle, Washington, USAVaccine and Infectious Diseases Division (VIDD), Fred Hutchinson Cancer Center, Seattle, Washington, USA1 Family Medicine, Univeristy of Washington, Seattle, WA, USAMYDAWA, Nairobi, KenyaIntroduction Pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV acquisition, but coverage remains low in high prevalence settings. Initiating and continuing PrEP via online pharmacies is a promising strategy to expand PrEP uptake but little is known about user preferences for this strategy. We describe methods for a discrete choice experiment (DCE) to assess preferences for PrEP delivery from an online pharmacy.Methods and analysis This cross-sectional study is conducted in Nairobi, Kenya, in partnership with MYDAWA, a private online pharmacy retailer with a planned sample size of >400 participants. Eligibility criteria are: ≥18 years, not known HIV-positive and interested in PrEP. Initial DCE attributes and levels were developed via literature review and stakeholder meetings. We conducted cognitive interviews to assess participant understanding of the DCE survey and refined the design. The final DCE used a D-efficient design and contained four attributes: PrEP eligibility assessment, HIV test type, clinical consultation type and user support options. Participants are presented with eight scenarios consisting of two hypothetical PrEP delivery services. The survey was piloted among 20 participants before being advertised on the MYDAWA website on pages displaying products indicating HIV risk (eg, HIV self-test kits). Interested participants call a study number and those screened eligible meet a research assistant in a convenient location to complete the survey. The DCE will be analysed using a conditional logit model to assess average preferences and mixed logit and latent class models to evaluate preference heterogeneity among subgroups.Ethics and dissemination This study was approved by the University of Washington Human Research Ethics Committee (STUDY00014011), the Kenya Medical Research Institute, Nairobi County (EOP/NMS/HS/128) and the Scientific and Ethics Review Unit in Kenya (KEMRI/RES/7/3/1). Participation in the DCE is voluntary and subject to completion of an electronic informed consent. Findings will be shared at international conferences and peer-reviewed publications, and via engagement meetings with stakeholders.https://bmjopen.bmj.com/content/13/4/e069195.full |
| spellingShingle | Melissa Latigo Mugambi Katrina F Ortblad Kenneth Ngure Catherine Kiptinness Fern Terris-Prestholt Monisha Sharma Andy Stergachis Yilin Chen Enrique M Saldarriaga Michalina A Montano Nicholas Thuo Maeve Rafferty Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experiment BMJ Open |
| title | Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experiment |
| title_full | Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experiment |
| title_fullStr | Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experiment |
| title_full_unstemmed | Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experiment |
| title_short | Assessing preferences for HIV pre-exposure prophylaxis (PrEP) delivery services via online pharmacies in Kenya: protocol for a discrete choice experiment |
| title_sort | assessing preferences for hiv pre exposure prophylaxis prep delivery services via online pharmacies in kenya protocol for a discrete choice experiment |
| url | https://bmjopen.bmj.com/content/13/4/e069195.full |
| work_keys_str_mv | AT melissalatigomugambi assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT katrinafortblad assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT kennethngure assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT catherinekiptinness assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT fernterrisprestholt assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT monishasharma assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT andystergachis assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT yilinchen assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT enriquemsaldarriaga assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT michalinaamontano assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT nicholasthuo assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment AT maeverafferty assessingpreferencesforhivpreexposureprophylaxisprepdeliveryservicesviaonlinepharmaciesinkenyaprotocolforadiscretechoiceexperiment |