Huaier Cream Protects against Adriamycin-Induced Nephropathy by Restoring Mitochondrial Function via PGC-1α Upregulation
The mechanism by which Huaier, a Chinese traditional medicine, protects podocytes remains unclear. We designed the present study to examine whether mitochondrial function restored by PGC-1α serves as the major target of Huaier cream in protecting ADR nephropathy. After ADR administration, the podocy...
Saved in:
| Main Authors: | Ruochen Che, Chunhua Zhu, Guixia Ding, Min Zhao, Mi Bai, Zhanjun Jia, Aihua Zhang, Songming Huang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2015/720383 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
M2c Macrophages Protect Mice from Adriamycin-Induced Nephropathy by Upregulating CD62L in Tregs
by: Junyu Lu, et al.
Published: (2022-01-01) -
Astragalin improved mitochondrial function through AMPK/PGC-1α pathway and alleviated renal injury in diabetic nephropathy
by: Yi Luo, et al.
Published: (2024-11-01) -
Tacrolimus repairs glomerular podocytes injury in rats with adriamycin induced nephropathy
by: CHEN Cai-ming, et al.
Published: (2020-01-01) -
HUWE1‐Mediated Degradation of MUTYH Facilitates DNA Damage and Mitochondrial Dysfunction to Promote Acute Kidney Injury
by: Yunwen Yang, et al.
Published: (2025-04-01) -
SLC25A35 enhances fatty acid oxidation and mitochondrial biogenesis to promote the carcinogenesis and progression of hepatocellular carcinoma by upregulating PGC-1α
by: Heng-Chao Yu, et al.
Published: (2025-03-01)