Diagnostic utility of IL-18 plasma levels in distinguishing abdominal from non-abdominal sepsis

Diagnostic utility of IL-18 plasma levels in distinguishing abdominal from non-abdominal sepsis

BackgroundAbdominal sepsis is a critical and high-risk condition in intensive care, characterized by diagnostic challenges, complex treatment, and high mortality. Non-specific symptoms and the difficulty of discriminating harmful bacteria from the normal flora complicate a timely diagnosis and treat...

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Main Authors: Anna Herminghaus, Mykola Totskyi, Christian Vollmer, Thomas Dimski, Timo Brandenburger, Anne Kuebart, Helen Rinderknecht, Christian B. Bergmann, Ina Vernikouskaya, Jasmin Maria Bülow, Nils Becker, Borna Relja
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
prediction
inflammation
cytokines
outcome
IL-18
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1591262/full
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