Role of Adenosine A2A Receptors in Modulating Synaptic Functions and Brain Levels of BDNF: a Possible Key Mechanism in the Pathophysiology of Huntington's Disease
In the last few years, accumulating evidence has shown the existence of an important cross-talk between adenosine A2A receptors (A2ARs) and brain-derived neurotrophic factor (BDNF). Not only are A2ARs involved in the mechanism of transactivation of BDNF receptor TrkB, they also modulate the effect o...
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| Main Authors: | Maria Teresa Tebano, Alberto Martire, Valentina Chiodi, Antonella Ferrante, Patrizia Popoli |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2010.164 |
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