Trends in Mendelian randomization in neurological disease research: a bibliometric analysis
Bibliometric analysis (BA) was used in this study to examine the current state and trends of Mendelian randomization (MR) in neurological disease research. The Web of Science database was searched between 1 January 2014 and 1 September 2024 to retrieve relevant literature. The volume of publications...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2025.1525481/full |
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| author | Shengnan Yin Kudelati Zakeer Zekun Ma Miaomiao Zhao Aierpati Maimaiti Zengliang Wang |
| author_facet | Shengnan Yin Kudelati Zakeer Zekun Ma Miaomiao Zhao Aierpati Maimaiti Zengliang Wang |
| author_sort | Shengnan Yin |
| collection | DOAJ |
| description | Bibliometric analysis (BA) was used in this study to examine the current state and trends of Mendelian randomization (MR) in neurological disease research. The Web of Science database was searched between 1 January 2014 and 1 September 2024 to retrieve relevant literature. The volume of publications, research themes, collaborative networks, and geographical distribution were studied quantitatively. A keyword co-occurrence analysis identified prominent research hotspots, including stroke, cardiovascular disease, and genome-wide association studies. Furthermore, highly cited literature underscored the potential of MR to elucidate causal relationships between genetic variants and health outcomes. International collaborative networks indicate that China, the United Kingdom, and the United States are the most engaged in collaborative efforts within this domain. The findings suggest that MR methods hold significant potential for applications in the investigation of neurological disorders, highlighting the necessity of international collaboration to foster scientific advancement. Future research should prioritize enhancing interdisciplinary collaboration and conducting comprehensive explorations of disease mechanisms to aid in prevention and treatment. |
| format | Article |
| id | doaj-art-314ef7e43b8f4fe6882ccf495748f6e7 |
| institution | Kabale University |
| issn | 1664-2295 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj-art-314ef7e43b8f4fe6882ccf495748f6e72025-08-20T03:30:29ZengFrontiers Media S.A.Frontiers in Neurology1664-22952025-07-011610.3389/fneur.2025.15254811525481Trends in Mendelian randomization in neurological disease research: a bibliometric analysisShengnan Yin0Kudelati Zakeer1Zekun Ma2Miaomiao Zhao3Aierpati Maimaiti4Zengliang Wang5Department of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaCollege of Health Management, Xinjiang Medical University, Urumqi, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaCollege of Health Management, Xinjiang Medical University, Urumqi, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaDepartment of Neurosurgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, ChinaBibliometric analysis (BA) was used in this study to examine the current state and trends of Mendelian randomization (MR) in neurological disease research. The Web of Science database was searched between 1 January 2014 and 1 September 2024 to retrieve relevant literature. The volume of publications, research themes, collaborative networks, and geographical distribution were studied quantitatively. A keyword co-occurrence analysis identified prominent research hotspots, including stroke, cardiovascular disease, and genome-wide association studies. Furthermore, highly cited literature underscored the potential of MR to elucidate causal relationships between genetic variants and health outcomes. International collaborative networks indicate that China, the United Kingdom, and the United States are the most engaged in collaborative efforts within this domain. The findings suggest that MR methods hold significant potential for applications in the investigation of neurological disorders, highlighting the necessity of international collaboration to foster scientific advancement. Future research should prioritize enhancing interdisciplinary collaboration and conducting comprehensive explorations of disease mechanisms to aid in prevention and treatment.https://www.frontiersin.org/articles/10.3389/fneur.2025.1525481/fullneurological diseaseMendelian randomizationbibliometric analysisreviewresearch trends |
| spellingShingle | Shengnan Yin Kudelati Zakeer Zekun Ma Miaomiao Zhao Aierpati Maimaiti Zengliang Wang Trends in Mendelian randomization in neurological disease research: a bibliometric analysis Frontiers in Neurology neurological disease Mendelian randomization bibliometric analysis review research trends |
| title | Trends in Mendelian randomization in neurological disease research: a bibliometric analysis |
| title_full | Trends in Mendelian randomization in neurological disease research: a bibliometric analysis |
| title_fullStr | Trends in Mendelian randomization in neurological disease research: a bibliometric analysis |
| title_full_unstemmed | Trends in Mendelian randomization in neurological disease research: a bibliometric analysis |
| title_short | Trends in Mendelian randomization in neurological disease research: a bibliometric analysis |
| title_sort | trends in mendelian randomization in neurological disease research a bibliometric analysis |
| topic | neurological disease Mendelian randomization bibliometric analysis review research trends |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2025.1525481/full |
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