A scRNA-seq reference contrasting living and early post-mortem human retina across diverse donor states

A scRNA-seq reference contrasting living and early post-mortem human retina across diverse donor states

Abstract Background Current human retina studies predominantly utilize post-mortem tissue, and the sample accessibility constraints make the characterization of the living human retina at single-cell resolution a challenge. Although single-nucleus RNA-seq expands the utility of frozen samples, it pr...

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Main Authors: Luning Yang, Yiwen Tao, Qi Pan, Tengda Cai, Yunyan Ye, Jianhui Liu, Yang Zhou, Yongqing Shao, Quanyong Yi, Zen Huat Lu, Lie Chen, Gareth McKay, Richard Rankin, Weihua Meng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Human Genomics
Subjects:
Single-cell RNA sequencing
Human retina
Transcriptomic atlas
Living tissue analysis
Retinal diversity
Online Access:https://doi.org/10.1186/s40246-025-00796-9
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