Fulminant pertussis in very young infants: two cases and review of the literature

Pertussis is one of the leading causes of death that can be prevented by vaccination. More than 600,000 deaths from pertussis occur annually, with a disproportionate number appearing in unvaccinated infants. Pertussis is particularly troublesome because it does not necessarily present itself...

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Main Authors: Muhammet Şükrü Paksu, Muhammet Akgün, Adil Karadağ, Nazik Aşılıoğlu, Nurşen Belet, Gülnar Şensoy
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2013-08-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/1525
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author Muhammet Şükrü Paksu
Muhammet Akgün
Adil Karadağ
Nazik Aşılıoğlu
Nurşen Belet
Gülnar Şensoy
author_facet Muhammet Şükrü Paksu
Muhammet Akgün
Adil Karadağ
Nazik Aşılıoğlu
Nurşen Belet
Gülnar Şensoy
author_sort Muhammet Şükrü Paksu
collection DOAJ
description Pertussis is one of the leading causes of death that can be prevented by vaccination. More than 600,000 deaths from pertussis occur annually, with a disproportionate number appearing in unvaccinated infants. Pertussis is particularly troublesome because it does not necessarily present itself in its commonly known classical stages. Therefore, in very young and non-immunized children, the disease may have a fulminant process characterized by severe leukocytosis, neurologic involvement and serious cardiopulmonary failure that can be accompanied by pulmonary hypertension, persistent hypoxia and death. This article describes two infants with fulminant pertussis; they were admitted for acute respiratory failure and severe leukocytosis and ultimately died from multi-organ failure.
format Article
id doaj-art-314b0f0b4a084bd0af2cda936d3b8ec4
institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 2013-08-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-314b0f0b4a084bd0af2cda936d3b8ec42025-08-20T03:00:54ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212013-08-01554Fulminant pertussis in very young infants: two cases and review of the literatureMuhammet Şükrü Paksu0Muhammet AkgünAdil KaradağNazik AşılıoğluNurşen BeletGülnar ŞensoyPediatric Intensive Care Unit, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey. sukrupaksu@yahoo.com. Pertussis is one of the leading causes of death that can be prevented by vaccination. More than 600,000 deaths from pertussis occur annually, with a disproportionate number appearing in unvaccinated infants. Pertussis is particularly troublesome because it does not necessarily present itself in its commonly known classical stages. Therefore, in very young and non-immunized children, the disease may have a fulminant process characterized by severe leukocytosis, neurologic involvement and serious cardiopulmonary failure that can be accompanied by pulmonary hypertension, persistent hypoxia and death. This article describes two infants with fulminant pertussis; they were admitted for acute respiratory failure and severe leukocytosis and ultimately died from multi-organ failure. https://turkjpediatr.org/article/view/1525
spellingShingle Muhammet Şükrü Paksu
Muhammet Akgün
Adil Karadağ
Nazik Aşılıoğlu
Nurşen Belet
Gülnar Şensoy
Fulminant pertussis in very young infants: two cases and review of the literature
The Turkish Journal of Pediatrics
title Fulminant pertussis in very young infants: two cases and review of the literature
title_full Fulminant pertussis in very young infants: two cases and review of the literature
title_fullStr Fulminant pertussis in very young infants: two cases and review of the literature
title_full_unstemmed Fulminant pertussis in very young infants: two cases and review of the literature
title_short Fulminant pertussis in very young infants: two cases and review of the literature
title_sort fulminant pertussis in very young infants two cases and review of the literature
url https://turkjpediatr.org/article/view/1525
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