Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway

Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway

IntroductionResearch has confirmed that Galangin can attenuate autophagy and protect dopaminergic neurons. This study aims to clarify whether Galangin attenuates dopaminergic neuron injury by regulating the PI3K/AKT pathway in Parkinson’s disease (PD) model mice.MethodsThe study explores the mitigat...

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Bibliographic Details
Main Authors: Liping Huang, Qiaofeng Li, Jingyi Wu, Yingying He, Junwei Huang, Sipeng Xie, Canfeng Yang, Qingling Ruan, Zhongliu Zhou, Minzhen Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
Galangin
Parkinson’s disease
autophagy
network analysis
transcriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1568002/full
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