Highly selective solid phase extraction of clonazepam from water using a urea modified MOF prior to HPLC analysis

Highly selective solid phase extraction of clonazepam from water using a urea modified MOF prior to HPLC analysis

Abstract The presence of pharmaceutical pollutants, such as clonazepam (CZP), in aquatic environments poses significant risks to ecosystems and human health. This study introduces a novel solid-phase extraction (SPE) method utilizing a urea-modified metal-organic framework (MIL-101(Fe)-Urea) for the...

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Bibliographic Details
Main Authors: Marzieh Sharifi-Rad, Asma Khoobi, Mostafa Khajeh, Massoud Kaykhaii, Ali Reza Oveisi
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Metal-organic framework
Solid-phase extraction
Drug
Environmental monitoring
Post-synthetic modification
Benzodiazepines
Online Access:https://doi.org/10.1038/s41598-025-07127-x
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