Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case Reports
Catheter implantation is the main cause of neonatal thrombosis. We present two cases of neonatal intracardiac thrombus associated with central venous catheters, each managed with different therapeutic approaches based on specific risk factors. In the first case, a large intracardiac thrombus, second...
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| Format: | Article |
| Language: | English |
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College of Medicine, Al-Nahrain University
2025-07-01
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| Series: | Baghdad Journal of Biochemistry and Applied Biological Sciences |
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| Online Access: | https://bjbabs.org/index.php/bjbabs/article/view/377 |
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| author | María F Preciado-Eguía Isaura G. Venzor-Pérez Maria Valeria Jiménez Báez |
| author_facet | María F Preciado-Eguía Isaura G. Venzor-Pérez Maria Valeria Jiménez Báez |
| author_sort | María F Preciado-Eguía |
| collection | DOAJ |
| description | Catheter implantation is the main cause of neonatal thrombosis. We present two cases of neonatal intracardiac thrombus associated with central venous catheters, each managed with different therapeutic approaches based on specific risk factors. In the first case, a large intracardiac thrombus, secondary to an umbilical venous catheter, was successfully treated with low molecular-weight heparin and antiplatelet therapy. In contrast, the second case, despite resolution with alteplase and heparin infusion, demonstrated thrombus recurrence despite catheter replacement and ongoing anticoagulation therapy. Currently, no standardized treatment guidelines exist for neonatal thrombosis. |
| format | Article |
| id | doaj-art-314427660d734351b2a6ea22ef4bad6d |
| institution | Kabale University |
| issn | 2706-9915 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | College of Medicine, Al-Nahrain University |
| record_format | Article |
| series | Baghdad Journal of Biochemistry and Applied Biological Sciences |
| spelling | doaj-art-314427660d734351b2a6ea22ef4bad6d2025-08-20T03:32:37ZengCollege of Medicine, Al-Nahrain UniversityBaghdad Journal of Biochemistry and Applied Biological Sciences2706-99152025-07-016317618210.47419/bjbabs.v6i03.377Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case ReportsMaría F Preciado-Eguía0https://orcid.org/0009-0008-9295-3998Isaura G. Venzor-Pérez1https://orcid.org/0009-0004-0391-274XMaria Valeria Jiménez Báez2https://orcid.org/0000-0002-9114-4741Pediatric Cardiology General Hospital of Cancun México, Universidad Autonoma de YucatánPediatric Cardiology General Hospital of Cancun México, Universidad Autonoma de YucatánMexican Institute Social Security Quintana Roo, Coordinator of Planning and Institutional LiaisonCatheter implantation is the main cause of neonatal thrombosis. We present two cases of neonatal intracardiac thrombus associated with central venous catheters, each managed with different therapeutic approaches based on specific risk factors. In the first case, a large intracardiac thrombus, secondary to an umbilical venous catheter, was successfully treated with low molecular-weight heparin and antiplatelet therapy. In contrast, the second case, despite resolution with alteplase and heparin infusion, demonstrated thrombus recurrence despite catheter replacement and ongoing anticoagulation therapy. Currently, no standardized treatment guidelines exist for neonatal thrombosis.https://bjbabs.org/index.php/bjbabs/article/view/377central venous catheterthrombosispreterm neonatecoagulationnewbornanticoagulation therapy |
| spellingShingle | María F Preciado-Eguía Isaura G. Venzor-Pérez Maria Valeria Jiménez Báez Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case Reports Baghdad Journal of Biochemistry and Applied Biological Sciences central venous catheter thrombosis preterm neonate coagulation newborn anticoagulation therapy |
| title | Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case Reports |
| title_full | Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case Reports |
| title_fullStr | Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case Reports |
| title_full_unstemmed | Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case Reports |
| title_short | Giant Intracardiac Thrombus Secondary to Central Venous Catheter in Neonates: About Two Case Reports |
| title_sort | giant intracardiac thrombus secondary to central venous catheter in neonates about two case reports |
| topic | central venous catheter thrombosis preterm neonate coagulation newborn anticoagulation therapy |
| url | https://bjbabs.org/index.php/bjbabs/article/view/377 |
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