Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review
Recent advancements in tuberculosis treatment research emphasize innovative strategies that enhance treatment efficacy, reduce adverse effects, and adhere to patient-centered care principles. As tuberculosis remains a significant global health challenge, integrating new and repurposed drugs presents...
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| Format: | Article |
| Language: | English |
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Ewha Womans University College of Medicine
2025-04-01
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| Series: | The Ewha Medical Journal |
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| Online Access: | http://www.e-emj.org/upload/pdf/emj-2025-00115.pdf |
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| author | Jinsoo Min Bruno B. Andrade Ju Sang Kim Yoolwon Jeong |
| author_facet | Jinsoo Min Bruno B. Andrade Ju Sang Kim Yoolwon Jeong |
| author_sort | Jinsoo Min |
| collection | DOAJ |
| description | Recent advancements in tuberculosis treatment research emphasize innovative strategies that enhance treatment efficacy, reduce adverse effects, and adhere to patient-centered care principles. As tuberculosis remains a significant global health challenge, integrating new and repurposed drugs presents promising avenues for more effective management, particularly against drug-resistant strains. Recently, the spectrum concept in tuberculosis infection and disease has emerged, underscoring the need for research aimed at developing treatment plans specific to each stage of the disease. The application of precision medicine to tailor treatments to individual patient profiles is crucial for addressing the diverse and complex nature of tuberculosis infections. Such personalized approaches are essential for optimizing therapeutic outcomes and improving patient adherence—both of which are vital for global tuberculosis eradication efforts. The role of tuberculosis cohort studies is also emphasized, as they provide critical data to support the development of these tailored treatment plans and deepen our understanding of disease progression and treatment response. To advance these innovations, a robust tuberculosis policy framework is required to foster the integration of research findings into practice, ensuring that treatment innovations are effectively translated into improved health outcomes worldwide. |
| format | Article |
| id | doaj-art-313f255abbd24a4b8a3d27faa4689a71 |
| institution | Kabale University |
| issn | 2234-3180 2234-2591 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Ewha Womans University College of Medicine |
| record_format | Article |
| series | The Ewha Medical Journal |
| spelling | doaj-art-313f255abbd24a4b8a3d27faa4689a712025-08-26T00:04:46ZengEwha Womans University College of MedicineThe Ewha Medical Journal2234-31802234-25912025-04-0148210.12771/emj.2025.001151612Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative reviewJinsoo Min0Bruno B. Andrade1Ju Sang Kim2Yoolwon Jeong3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaLaboratory of Clinical and Translational Research, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, BrazilDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaDepartment of Preventive Medicine, Dankook University Hospital, Cheonan, KoreaRecent advancements in tuberculosis treatment research emphasize innovative strategies that enhance treatment efficacy, reduce adverse effects, and adhere to patient-centered care principles. As tuberculosis remains a significant global health challenge, integrating new and repurposed drugs presents promising avenues for more effective management, particularly against drug-resistant strains. Recently, the spectrum concept in tuberculosis infection and disease has emerged, underscoring the need for research aimed at developing treatment plans specific to each stage of the disease. The application of precision medicine to tailor treatments to individual patient profiles is crucial for addressing the diverse and complex nature of tuberculosis infections. Such personalized approaches are essential for optimizing therapeutic outcomes and improving patient adherence—both of which are vital for global tuberculosis eradication efforts. The role of tuberculosis cohort studies is also emphasized, as they provide critical data to support the development of these tailored treatment plans and deepen our understanding of disease progression and treatment response. To advance these innovations, a robust tuberculosis policy framework is required to foster the integration of research findings into practice, ensuring that treatment innovations are effectively translated into improved health outcomes worldwide.http://www.e-emj.org/upload/pdf/emj-2025-00115.pdfdrug-related side effects and adverse reactionsiatrogenic diseaseprecision medicinetreatment outcometuberculosis |
| spellingShingle | Jinsoo Min Bruno B. Andrade Ju Sang Kim Yoolwon Jeong Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review The Ewha Medical Journal drug-related side effects and adverse reactions iatrogenic disease precision medicine treatment outcome tuberculosis |
| title | Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review |
| title_full | Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review |
| title_fullStr | Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review |
| title_full_unstemmed | Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review |
| title_short | Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review |
| title_sort | bridging science and policy in tuberculosis treatment through innovations in precision medicine drug development and cohort research a narrative review |
| topic | drug-related side effects and adverse reactions iatrogenic disease precision medicine treatment outcome tuberculosis |
| url | http://www.e-emj.org/upload/pdf/emj-2025-00115.pdf |
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