HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome.

HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome.

HIV-1 Vpr is a virion-associated protein. Its activities link to viral pathogenesis and disease progression of HIV-infected patients. In vitro, Vpr moderately activates HIV-1 replication in proliferating T cells, but it is required for efficient viral infection and replication in vivo in non-dividin...

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Bibliographic Details
Main Authors: Ge Li, Robert T Elder, Larisa Dubrovsky, Dong Liang, Tatiana Pushkarsky, Karen Chiu, Tao Fan, Josephine Sire, Michael Bukrinsky, Richard Y Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011371&type=printable
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