A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma
58-year-old female was admitted to our hospital complaining isolated proteinuria of 1.7 g/day. Abdominal echography showed right-sided unilateral hydronephrosis, and computed tomography pointed out a tumor of the right renal pelvis, suggesting cancer of renal pelvis. The right nephroureterectomy was...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2011/373480 |
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| author | Masanori Sakakima Yoshihide Fujigaki Hideo Yasuda Akashi Togawa Tomoyuki Fujikura Atsushi Otsuka Seiichiro Ozono Akira Hishida |
| author_facet | Masanori Sakakima Yoshihide Fujigaki Hideo Yasuda Akashi Togawa Tomoyuki Fujikura Atsushi Otsuka Seiichiro Ozono Akira Hishida |
| author_sort | Masanori Sakakima |
| collection | DOAJ |
| description | 58-year-old female was admitted to our hospital complaining isolated proteinuria of 1.7 g/day. Abdominal echography showed right-sided unilateral hydronephrosis, and computed tomography pointed out a tumor of the right renal pelvis, suggesting cancer of renal pelvis. The right nephroureterectomy was carried out. Pathological diagnosis was urothelial carcinoma. Renal tissue revealed no apparent glomerulopathy with tubular atrophy, interstitial fibrosis, and mildly-to-moderately interstitial mononuclear cell infiltration. Immunofluorescence study showed no deposition of immunoreactanct, and electron microscopy showed almost normal glomerulus without electron dense deposit. Proteinuria disappeared within 6 days after the operation. Moderate amount of proteinuria in our patient was probably caused by secreted protein from urothelial carcinoma. This condition is rare but should be taken into account in patients with even moderate amount of proteinuria. |
| format | Article |
| id | doaj-art-313c0a2ffc354dc4aeebbdf5110bdec0 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-313c0a2ffc354dc4aeebbdf5110bdec02025-02-03T05:47:58ZengWileyCase Reports in Nephrology2090-66412090-665X2011-01-01201110.1155/2011/373480373480A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial CarcinomaMasanori Sakakima0Yoshihide Fujigaki1Hideo Yasuda2Akashi Togawa3Tomoyuki Fujikura4Atsushi Otsuka5Seiichiro Ozono6Akira Hishida7The First Department of Medicine, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu 431-3192, JapanThe First Department of Medicine, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu 431-3192, JapanThe First Department of Medicine, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu 431-3192, JapanThe First Department of Medicine, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu 431-3192, JapanThe First Department of Medicine, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu 431-3192, JapanDepartment of Urology, Hamamatsu University School of Medicine, Hamamatsu, JapanDepartment of Urology, Hamamatsu University School of Medicine, Hamamatsu, JapanThe First Department of Medicine, Hamamatsu University School of Medicine, Higashi-ku, Hamamatsu 431-3192, Japan58-year-old female was admitted to our hospital complaining isolated proteinuria of 1.7 g/day. Abdominal echography showed right-sided unilateral hydronephrosis, and computed tomography pointed out a tumor of the right renal pelvis, suggesting cancer of renal pelvis. The right nephroureterectomy was carried out. Pathological diagnosis was urothelial carcinoma. Renal tissue revealed no apparent glomerulopathy with tubular atrophy, interstitial fibrosis, and mildly-to-moderately interstitial mononuclear cell infiltration. Immunofluorescence study showed no deposition of immunoreactanct, and electron microscopy showed almost normal glomerulus without electron dense deposit. Proteinuria disappeared within 6 days after the operation. Moderate amount of proteinuria in our patient was probably caused by secreted protein from urothelial carcinoma. This condition is rare but should be taken into account in patients with even moderate amount of proteinuria.http://dx.doi.org/10.1155/2011/373480 |
| spellingShingle | Masanori Sakakima Yoshihide Fujigaki Hideo Yasuda Akashi Togawa Tomoyuki Fujikura Atsushi Otsuka Seiichiro Ozono Akira Hishida A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma Case Reports in Nephrology |
| title | A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma |
| title_full | A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma |
| title_fullStr | A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma |
| title_full_unstemmed | A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma |
| title_short | A Case with Significant Proteinuria Caused by Secreted Protein from Urothelial Carcinoma |
| title_sort | case with significant proteinuria caused by secreted protein from urothelial carcinoma |
| url | http://dx.doi.org/10.1155/2011/373480 |
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