New Diagnostic Candidate Molecular Biomarkers of Acute Respiratory Distress Syndrome
Editorial dedicated to the development of the algorithm of diagnosis and prognosis of acute respiratory distress syndrome (ARDS), based on the use of recent data (2012—2014) from the V. A. Negovsky Institute of General reanimatology. Modern approaches to the diagnosis and treatment of ARDS are discu...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2014-08-01
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| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1408 |
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| Summary: | Editorial dedicated to the development of the algorithm of diagnosis and prognosis of acute respiratory distress syndrome (ARDS), based on the use of recent data (2012—2014) from the V. A. Negovsky Institute of General reanimatology. Modern approaches to the diagnosis and treatment of ARDS are discussed. Available modern data including results of own recent investigation have clearly demonstrated the potential of quantifying surfactant proteins SPA and SPD, which pro duced by cells of the respiratory epithelium, for the early diagnosis and prognosis of ARDS. A new algorithm for diagnosis and prognosis of ARDS based on a sequential quantification of SPA and SPD molecules in the plasma of patients in crit ical conditions is suggested. Circulating SPA and SPD are considered as valuable candidate biomarkers for developingmultiparametric panel of biomarkers for diagnosis and prognosis of ARDS in patients with lifethreatening critical illness. |
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| ISSN: | 1813-9779 2411-7110 |