Neuropsychiatric adverse events in people with HIV initiating a new integrase strand transfer inhibitor-based regimen in Italy: findings from the NEURO-INSTI study

Neuropsychiatric adverse events in people with HIV initiating a new integrase strand transfer inhibitor-based regimen in Italy: findings from the NEURO-INSTI study

Abstract Background Although clinical trials reported a low and comparable rate of central nervous system (CNS)/neuropsychiatric (NP) disturbances among people with HIV (PWH) receiving integrase strand transfer inhibitors (INSTI) or other antiretroviral therapy (ART), higher rates of these disturban...

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Main Authors: Nicola Squillace, Elena Delfina Ricci, Giancarlo Orofino, Gabriele Forcina, Laura Albini, Barbara Menzaghi, Giuseppe Vittorio De Socio, Stefania Piconi, Paolo Maggi, Giordano Madeddu, Giovanni Francesco Pellicanò, Eleonora Sarchi, Benedetto Maurizio Celesia, Filippo Lagi, Elena Salomoni, Antonio Di Biagio, Paolo Bonfanti
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Infectious Diseases
Subjects:
CNS adverse events
Neurologic disorders
Psychiatric disorders
HIV
Integrase strand transfer inhibitors
Bictegravir
Online Access:https://doi.org/10.1186/s12879-025-11090-3
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