Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen

Introduction. Bruxism is a movement disorder characterized by grinding and clenching of the teeth. Etiology of bruxism can be divided into three groups: psychosocial factors, peripheral factors, and pathophysiological factors. Methods. The clinical investigation was conducted at King Khaled Hospital...

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Main Authors: A. Bruce Janati, Naif Saad ALGhasab, Fahad Saad ALGhassab
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2013/129234
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author A. Bruce Janati
Naif Saad ALGhasab
Fahad Saad ALGhassab
author_facet A. Bruce Janati
Naif Saad ALGhasab
Fahad Saad ALGhassab
author_sort A. Bruce Janati
collection DOAJ
description Introduction. Bruxism is a movement disorder characterized by grinding and clenching of the teeth. Etiology of bruxism can be divided into three groups: psychosocial factors, peripheral factors, and pathophysiological factors. Methods. The clinical investigation was conducted at King Khaled Hospital in Hail, Saudi Arabia, in 2012. Results. A 16-year-old Saudi female was brought to the hospital in a comatose state and with generalized convulsive seizures secondary to acute anoxic encephalopathy. In the third week of hospitalization, while still in a state of akinetic mutism, she developed incessant bruxism which responded favorably to a GABA receptor agonist (baclofen). Conclusion. Our data support the hypothesis that bruxism emanates from imbalance or dysregulation of the neurotransmitter system. Larger scale studies will be needed to confirm this hypothesis.
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series Case Reports in Dentistry
spelling doaj-art-3133474b07e342c4b0a2b997417fcfbc2025-08-20T02:38:53ZengWileyCase Reports in Dentistry2090-64472090-64552013-01-01201310.1155/2013/129234129234Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with BaclofenA. Bruce Janati0Naif Saad ALGhasab1Fahad Saad ALGhassab2Center for Neurology of Fairfax, VA 22031, USAKing Faisal Specialist Hospital, Riyadh, Saudi ArabiaHail University, 81442 Hail, Saudi ArabiaIntroduction. Bruxism is a movement disorder characterized by grinding and clenching of the teeth. Etiology of bruxism can be divided into three groups: psychosocial factors, peripheral factors, and pathophysiological factors. Methods. The clinical investigation was conducted at King Khaled Hospital in Hail, Saudi Arabia, in 2012. Results. A 16-year-old Saudi female was brought to the hospital in a comatose state and with generalized convulsive seizures secondary to acute anoxic encephalopathy. In the third week of hospitalization, while still in a state of akinetic mutism, she developed incessant bruxism which responded favorably to a GABA receptor agonist (baclofen). Conclusion. Our data support the hypothesis that bruxism emanates from imbalance or dysregulation of the neurotransmitter system. Larger scale studies will be needed to confirm this hypothesis.http://dx.doi.org/10.1155/2013/129234
spellingShingle A. Bruce Janati
Naif Saad ALGhasab
Fahad Saad ALGhassab
Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen
Case Reports in Dentistry
title Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen
title_full Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen
title_fullStr Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen
title_full_unstemmed Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen
title_short Bruxism Associated with Anoxic Encephalopathy: Successful Treatment with Baclofen
title_sort bruxism associated with anoxic encephalopathy successful treatment with baclofen
url http://dx.doi.org/10.1155/2013/129234
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