Molecular mechanisms of dose-dependent regulation of hepatic lipid metabolism by BaP through modulation of AhR binding to XRE1 or XRE3
Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon and a potent environmental pollutant, has been implicated in the dysregulation of lipid metabolism and metabolic diseases, warranting investigation into its effects on liver functions, particularly regarding fibroblast growth factor 21 (FGF21)...
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| Main Authors: | Mengdi Zhang, Xiaoli Lv, Chaojie Wang, Lei Wang, Han Wang, Xue Wang, Yulu Du, Jun Li, Xiuli Han, Lei Fan, Yuxia Hu, Tuya Bai, Weizhong Huangfu, Fuhou Chang |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1595566/full |
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