Factors related to depression among transgender women: A systematic review

Background & Aim: Transgender women represent a vulnerable population with a high rate of depression. This systematic review aims to identify and analyze the factors associated with depression in this population. Methods & Materials: The research protocol was registered with PROSPERO. A sys...

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Main Authors: Patcharin Krongtham, Ratsiri Thato, Penpaktr Uthis
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2025-03-01
Series:Nursing Practice Today
Subjects:
Online Access:https://npt.tums.ac.ir/index.php/npt/article/view/3720
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author Patcharin Krongtham
Ratsiri Thato
Penpaktr Uthis
author_facet Patcharin Krongtham
Ratsiri Thato
Penpaktr Uthis
author_sort Patcharin Krongtham
collection DOAJ
description Background & Aim: Transgender women represent a vulnerable population with a high rate of depression. This systematic review aims to identify and analyze the factors associated with depression in this population. Methods & Materials: The research protocol was registered with PROSPERO. A systematic search was conducted using PubMed, MEDLINE, Scopus, and ProQuest for studies published between 2014 and 2024. Relevant studies focusing on depression and related factors in transgender women were selected. Data extraction focused on identified factors associated with depression. The reporting of this review adhered to PRISMA guidelines, and the quality of included studies was appraised using JBI’s critical appraisal tools. A narrative synthesis was conducted to synthesize the findings. Results: From 2,511 records identified in the database, 14 cross-sectional studies were included in the review. The analysis revealed three primary categories of factors related to depression: demographic, psychological, and sociological factors. Key demographic factors included age and insufficient income, both of which were at increased risk of depression. Psychological factors such as self-stigma and self-esteem were associated with higher depression rates. Sociological factors, including family support, peer support, and violence, were also significant predictors of depression in transgender women. Conclusion: Depression in transgender women is influenced by a complex interaction of demographic, psychological, and sociological factors. These findings underscore the need for tailored nursing interventions that incorporate mental health support.
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spelling doaj-art-3124f88eec3243e099d671ce25e628102025-08-20T03:03:41ZengTehran University of Medical SciencesNursing Practice Today2383-11542383-11622025-03-0112210.18502/npt.v12i2.18335Factors related to depression among transgender women: A systematic reviewPatcharin Krongtham0Ratsiri Thato1Penpaktr Uthis2Faculty of Nursing, Chulalongkorn University, Bangkok, ThailandFaculty of Nursing, Chulalongkorn University, Bangkok, ThailandFaculty of Nursing, Chulalongkorn University, Bangkok, Thailand Background & Aim: Transgender women represent a vulnerable population with a high rate of depression. This systematic review aims to identify and analyze the factors associated with depression in this population. Methods & Materials: The research protocol was registered with PROSPERO. A systematic search was conducted using PubMed, MEDLINE, Scopus, and ProQuest for studies published between 2014 and 2024. Relevant studies focusing on depression and related factors in transgender women were selected. Data extraction focused on identified factors associated with depression. The reporting of this review adhered to PRISMA guidelines, and the quality of included studies was appraised using JBI’s critical appraisal tools. A narrative synthesis was conducted to synthesize the findings. Results: From 2,511 records identified in the database, 14 cross-sectional studies were included in the review. The analysis revealed three primary categories of factors related to depression: demographic, psychological, and sociological factors. Key demographic factors included age and insufficient income, both of which were at increased risk of depression. Psychological factors such as self-stigma and self-esteem were associated with higher depression rates. Sociological factors, including family support, peer support, and violence, were also significant predictors of depression in transgender women. Conclusion: Depression in transgender women is influenced by a complex interaction of demographic, psychological, and sociological factors. These findings underscore the need for tailored nursing interventions that incorporate mental health support. https://npt.tums.ac.ir/index.php/npt/article/view/3720depression; transgender women; systematic review
spellingShingle Patcharin Krongtham
Ratsiri Thato
Penpaktr Uthis
Factors related to depression among transgender women: A systematic review
Nursing Practice Today
depression; transgender women; systematic review
title Factors related to depression among transgender women: A systematic review
title_full Factors related to depression among transgender women: A systematic review
title_fullStr Factors related to depression among transgender women: A systematic review
title_full_unstemmed Factors related to depression among transgender women: A systematic review
title_short Factors related to depression among transgender women: A systematic review
title_sort factors related to depression among transgender women a systematic review
topic depression; transgender women; systematic review
url https://npt.tums.ac.ir/index.php/npt/article/view/3720
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AT ratsirithato factorsrelatedtodepressionamongtransgenderwomenasystematicreview
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