Novel Arf1 Inhibitors Drive Cancer Stem Cell Aging and Potentiate Anti‐Tumor Immunity
Abstract The small G protein Arf1 has been identified as playing a selective role in supporting cancer stem cells (CSCs), making it an attractive target for cancer therapy. However, the current Arf1 inhibitors have limited translational potential due to their high toxicity and low specificity. In th...
Saved in:
| Main Authors: | Yuetong Wang, Qiaoming Li, Yahui Ding, Chenfei Luo, Jun Yang, Na Wang, Ning Jiang, Tiange Yao, Guohao Wang, Guoming Shi, Steven X. Hou |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-10-01
|
| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202404442 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Arfs on the Golgi: four conductors, one orchestra
by: Selma Yilmaz Dejgaard, et al.
Published: (2025-07-01) -
Accumulation of Damaging Lipids in the Arf1‐Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia
by: Xu Li, et al.
Published: (2025-04-01) -
Methuosis key gene ARF6 as a diagnostic, prognostic and immunotherapeutic marker for prostate cancer: based on a comprehensive pan-cancer multi-omics analysis
by: Yongjin Yang, et al.
Published: (2025-05-01) -
Genome-wide identification and expression pattern analysis of auxin response factor (ARF) genes in Chionanthus retusus and functional characterization of CrARF37 in terms of its effect on flower shape
by: Jinnan Wang, et al.
Published: (2025-08-01) -
Novel long noncoding lncARF mediated hyperhomocysteinemia-induced atherosclerosis via autophagy inhibition in foam cells
by: Ning Ding, et al.
Published: (2025-07-01)