Cardiovascular-kidney-metabolic Syndrome: a current and urgent concept

Abstract The concept of cardiovascular-kidney-metabolic health is based on the idea of a multifaceted interaction among several cardiovascular, renal, and metabolic factors. Alterations in this complex interaction have a significant impact on morbidity and mortality. The ramifications of poor cardio...

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Main Authors: Andrea Pio de Abreu, Luciano Ferreira Drager, Madson Queiroz Almeida, Luiz Aparecido Bortolotto, Heno Ferreira Lopes
Format: Article
Language:English
Published: Sociedade Brasileira de Nefrologia 2025-05-01
Series:Brazilian Journal of Nephrology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002025000200601&lng=en&tlng=en
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author Andrea Pio de Abreu
Luciano Ferreira Drager
Madson Queiroz Almeida
Luiz Aparecido Bortolotto
Heno Ferreira Lopes
author_facet Andrea Pio de Abreu
Luciano Ferreira Drager
Madson Queiroz Almeida
Luiz Aparecido Bortolotto
Heno Ferreira Lopes
author_sort Andrea Pio de Abreu
collection DOAJ
description Abstract The concept of cardiovascular-kidney-metabolic health is based on the idea of a multifaceted interaction among several cardiovascular, renal, and metabolic factors. Alterations in this complex interaction have a significant impact on morbidity and mortality. The ramifications of poor cardiovascular-kidney-metabolic health are far-reaching, with a notable clinical impact. A considerable proportion of the population is affected by precarious cardiovascular, renal, and metabolic health, and individuals with adverse social determinants of health endure an even greater burden. To this end, it is essential to develop an approach that incorporates metabolic staging and prioritizes lifelong prevention. Equally imperative is integrating the social determinants of health into care models for Cardiovascular-kidney-metabolic syndrome, facilitating patient-centered interdisciplinary care. The American Heart Association (AHA) provides guidelines on the definition, staging, paradigms, and holistic approaches to the management of patients with this syndrome. Furthermore, it offers a comprehensive framework for effectively and equitably improving the cardiovascular, kidney, and metabolic health of the population.
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issn 2175-8239
language English
publishDate 2025-05-01
publisher Sociedade Brasileira de Nefrologia
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series Brazilian Journal of Nephrology
spelling doaj-art-311ec0cd5ca9427cb6c1f2b30954433f2025-08-20T03:08:02ZengSociedade Brasileira de NefrologiaBrazilian Journal of Nephrology2175-82392025-05-0147210.1590/2175-8239-jbn-2024-0277enCardiovascular-kidney-metabolic Syndrome: a current and urgent conceptAndrea Pio de Abreuhttps://orcid.org/0000-0002-5118-7990Luciano Ferreira Dragerhttps://orcid.org/0000-0002-2081-6846Madson Queiroz Almeidahttps://orcid.org/0000-0002-2957-6148Luiz Aparecido Bortolottohttps://orcid.org/0000-0002-4865-6442Heno Ferreira Lopeshttps://orcid.org/0000-0002-9591-3093Abstract The concept of cardiovascular-kidney-metabolic health is based on the idea of a multifaceted interaction among several cardiovascular, renal, and metabolic factors. Alterations in this complex interaction have a significant impact on morbidity and mortality. The ramifications of poor cardiovascular-kidney-metabolic health are far-reaching, with a notable clinical impact. A considerable proportion of the population is affected by precarious cardiovascular, renal, and metabolic health, and individuals with adverse social determinants of health endure an even greater burden. To this end, it is essential to develop an approach that incorporates metabolic staging and prioritizes lifelong prevention. Equally imperative is integrating the social determinants of health into care models for Cardiovascular-kidney-metabolic syndrome, facilitating patient-centered interdisciplinary care. The American Heart Association (AHA) provides guidelines on the definition, staging, paradigms, and holistic approaches to the management of patients with this syndrome. Furthermore, it offers a comprehensive framework for effectively and equitably improving the cardiovascular, kidney, and metabolic health of the population.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002025000200601&lng=en&tlng=enCardiovascular DiseasesRenal Insufficiency, ChronicObesityChronic InflammationOxidative Stress
spellingShingle Andrea Pio de Abreu
Luciano Ferreira Drager
Madson Queiroz Almeida
Luiz Aparecido Bortolotto
Heno Ferreira Lopes
Cardiovascular-kidney-metabolic Syndrome: a current and urgent concept
Brazilian Journal of Nephrology
Cardiovascular Diseases
Renal Insufficiency, Chronic
Obesity
Chronic Inflammation
Oxidative Stress
title Cardiovascular-kidney-metabolic Syndrome: a current and urgent concept
title_full Cardiovascular-kidney-metabolic Syndrome: a current and urgent concept
title_fullStr Cardiovascular-kidney-metabolic Syndrome: a current and urgent concept
title_full_unstemmed Cardiovascular-kidney-metabolic Syndrome: a current and urgent concept
title_short Cardiovascular-kidney-metabolic Syndrome: a current and urgent concept
title_sort cardiovascular kidney metabolic syndrome a current and urgent concept
topic Cardiovascular Diseases
Renal Insufficiency, Chronic
Obesity
Chronic Inflammation
Oxidative Stress
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002025000200601&lng=en&tlng=en
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