Risk Factors for Mortality of Pediatric Patients Without Underlying Diseases
In this study, we investigated the risk factors for in-hospital mortality of children beyond infancy with and without underlying diseases. Methods: We performed a retrospective review of all deceased patients aged 1–18 years at Chang-Gung Memorial Hospital-Kaohsiung from 2000 to 2009. The patients w...
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| Format: | Article |
| Language: | English |
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Elsevier
2011-02-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S187595721000015X |
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| author | Ling-Sai Chang Ho-Chang Kuo Chieh-Chiang Wu Hong-Ren Yu Lin Wang Hsueh-Wen Chang Kuender D. Yang |
| author_facet | Ling-Sai Chang Ho-Chang Kuo Chieh-Chiang Wu Hong-Ren Yu Lin Wang Hsueh-Wen Chang Kuender D. Yang |
| author_sort | Ling-Sai Chang |
| collection | DOAJ |
| description | In this study, we investigated the risk factors for in-hospital mortality of children beyond infancy with and without underlying diseases.
Methods: We performed a retrospective review of all deceased patients aged 1–18 years at Chang-Gung Memorial Hospital-Kaohsiung from 2000 to 2009. The patients were divided into two groups; those with and without underlying diseases. Demographic data, clinical characteristics, and initial laboratory data were analyzed to correlate the risk factors for mortality of pediatric patients with and without underlying diseases.
Results: A total of 131 deceased children were found from 2000 to 2009. Forty children were previously healthy (without underlying diseases), whereas 91 had previous underlying diseases. Children with cardiovascular or central nervous system (CNS) infections had a significantly greater risk of mortality than did those without underlying diseases (p=0.004 and p=0.0004, respectively). More cardiovascular and fewer hematologic abnormalities at admission were found in patients without underlying diseases. In multiple logistic regression, it was found that cardiovascular (p=0.006) or CNS infections (p=0.012), consciousness change at admission (p=0.013), and higher liver enzyme levels were most significantly associated with deceased children without underlying diseases.
Conclusion: Results from this study suggest that mortality in pediatric patients without underlying diseases is most frequently found in younger children with CNS and cardiovascular infections, consciousness change, and high liver enzyme levels at admission. Results from this analysis will provide information for the awareness of fatal outcomes in previously healthy children. |
| format | Article |
| id | doaj-art-30f6f52a17e64476aecbac09028a95d5 |
| institution | Kabale University |
| issn | 1875-9572 |
| language | English |
| publishDate | 2011-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-30f6f52a17e64476aecbac09028a95d52025-08-20T03:49:12ZengElsevierPediatrics and Neonatology1875-95722011-02-01521343710.1016/j.pedneo.2010.12.007Risk Factors for Mortality of Pediatric Patients Without Underlying DiseasesLing-Sai Chang0Ho-Chang Kuo1Chieh-Chiang Wu2Hong-Ren Yu3Lin Wang4Hsueh-Wen Chang5Kuender D. Yang6Division of Pediatric Allergy and Immunology, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University, Kaohsiung, TaiwanDivision of Pediatric Allergy and Immunology, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University, Kaohsiung, TaiwanDivision of Pediatric Allergy and Immunology, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University, Kaohsiung, TaiwanDivision of Pediatric Allergy and Immunology, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University, Kaohsiung, TaiwanDivision of Pediatric Allergy and Immunology, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University, Kaohsiung, TaiwanDepartment of Medical Research, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, TaiwanDivision of Pediatric Allergy and Immunology, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Graduate Institute of Clinical Medical Science, Chang Gung University, Kaohsiung, TaiwanIn this study, we investigated the risk factors for in-hospital mortality of children beyond infancy with and without underlying diseases. Methods: We performed a retrospective review of all deceased patients aged 1–18 years at Chang-Gung Memorial Hospital-Kaohsiung from 2000 to 2009. The patients were divided into two groups; those with and without underlying diseases. Demographic data, clinical characteristics, and initial laboratory data were analyzed to correlate the risk factors for mortality of pediatric patients with and without underlying diseases. Results: A total of 131 deceased children were found from 2000 to 2009. Forty children were previously healthy (without underlying diseases), whereas 91 had previous underlying diseases. Children with cardiovascular or central nervous system (CNS) infections had a significantly greater risk of mortality than did those without underlying diseases (p=0.004 and p=0.0004, respectively). More cardiovascular and fewer hematologic abnormalities at admission were found in patients without underlying diseases. In multiple logistic regression, it was found that cardiovascular (p=0.006) or CNS infections (p=0.012), consciousness change at admission (p=0.013), and higher liver enzyme levels were most significantly associated with deceased children without underlying diseases. Conclusion: Results from this study suggest that mortality in pediatric patients without underlying diseases is most frequently found in younger children with CNS and cardiovascular infections, consciousness change, and high liver enzyme levels at admission. Results from this analysis will provide information for the awareness of fatal outcomes in previously healthy children.http://www.sciencedirect.com/science/article/pii/S187595721000015Xmortalitypediatricrisk factors |
| spellingShingle | Ling-Sai Chang Ho-Chang Kuo Chieh-Chiang Wu Hong-Ren Yu Lin Wang Hsueh-Wen Chang Kuender D. Yang Risk Factors for Mortality of Pediatric Patients Without Underlying Diseases Pediatrics and Neonatology mortality pediatric risk factors |
| title | Risk Factors for Mortality of Pediatric Patients Without Underlying Diseases |
| title_full | Risk Factors for Mortality of Pediatric Patients Without Underlying Diseases |
| title_fullStr | Risk Factors for Mortality of Pediatric Patients Without Underlying Diseases |
| title_full_unstemmed | Risk Factors for Mortality of Pediatric Patients Without Underlying Diseases |
| title_short | Risk Factors for Mortality of Pediatric Patients Without Underlying Diseases |
| title_sort | risk factors for mortality of pediatric patients without underlying diseases |
| topic | mortality pediatric risk factors |
| url | http://www.sciencedirect.com/science/article/pii/S187595721000015X |
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