Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan
Dermatophytosis, also known as Tinea infection, remains a significant interdisciplinary concern worldwide. This dermatophyte infection may be more serious in individuals with underlying somatic diseases, immunodeficiencies, endocrine disorders, or chronic illnesses. This study analyzed 313 patients...
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2025-01-01
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| author | Alma Aimoldina Ainura Smagulova Gulnar Batpenova Nellie Konnikov Togzhan Algazina Zulfiya Jetpisbayeva Dinara Azanbayeva Darkhan Amantayev Vladimir Kiyan |
| author_facet | Alma Aimoldina Ainura Smagulova Gulnar Batpenova Nellie Konnikov Togzhan Algazina Zulfiya Jetpisbayeva Dinara Azanbayeva Darkhan Amantayev Vladimir Kiyan |
| author_sort | Alma Aimoldina |
| collection | DOAJ |
| description | Dermatophytosis, also known as Tinea infection, remains a significant interdisciplinary concern worldwide. This dermatophyte infection may be more serious in individuals with underlying somatic diseases, immunodeficiencies, endocrine disorders, or chronic illnesses. This study analyzed 313 patients with suspected dermatophytosis. Data were gathered through questionnaires and medical records were reviewed. Biological samples were cultured on Sabouraud dextrose agar, and PCR was employed to assess the genetic diversity of strains. Statistical analysis was conducted using SPSS version 26. The overall prevalence of dermatophytosis in the cohort was 30.4%. Among the cultured isolates, 73.7% were identified as <i>Microsporum canis</i>, while 26.3% were identified as <i>Trichophyton</i> species, including <i>T. mentagrophytes</i>, <i>T. tonsurans</i>, and <i>T. verrucosum</i>. Several factors were significantly associated with an increased risk of dermatophytosis, including the following: male gender (AOR = 1.97), age 1–10 years (AOR = 3.80), living in rural areas (AOR = 2.30), visiting public bathhouses (AOR = 2.32), visiting massage parlors (AOR = 1.39), contact with cats (AOR = 2.32), family history of dermatophytosis (AOR = 3.04), and sexual contact with an infected or unknown partner (AOR = 3.08). Dermatophytosis was identified in approximately one third of the patients by culture (30.4%), with the risk heightened in individuals under 10 years old (43.6%), those living in rural areas (33.3%), and those with a family history of dermatophytosis (35.7%) or close contact with cats (39.4%). The findings underscore the need for strengthened preventive measures and targeted diagnostics, particularly among high-risk groups. |
| format | Article |
| id | doaj-art-30ed7d3451f8405a9b3a99d2d95bbc91 |
| institution | Kabale University |
| issn | 2309-608X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj-art-30ed7d3451f8405a9b3a99d2d95bbc912025-01-24T13:37:25ZengMDPI AGJournal of Fungi2309-608X2025-01-011116510.3390/jof11010065Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, KazakhstanAlma Aimoldina0Ainura Smagulova1Gulnar Batpenova2Nellie Konnikov3Togzhan Algazina4Zulfiya Jetpisbayeva5Dinara Azanbayeva6Darkhan Amantayev7Vladimir Kiyan8Department of Dermatovenereology and Dermatocosmetology, Astana Medical University, Astana 010011, KazakhstanLaboratory of Biodiversity and Genetic Resources, National Center for Biotechnology, Astana 010011, KazakhstanDepartment of Dermatovenereology and Dermatocosmetology, Astana Medical University, Astana 010011, KazakhstanDermatology Section, Department of Medicine, VA Boston Healthcare System, Boston, MA 02130, USADepartment of Dermatovenereology and Dermatocosmetology, Astana Medical University, Astana 010011, KazakhstanDepartment of Dermatovenereology and Dermatocosmetology, Astana Medical University, Astana 010011, KazakhstanDepartment of Dermatovenereology and Dermatocosmetology, Astana Medical University, Astana 010011, KazakhstanDepartment of Dermatovenereology and Dermatocosmetology, Astana Medical University, Astana 010011, KazakhstanLaboratory of Biodiversity and Genetic Resources, National Center for Biotechnology, Astana 010011, KazakhstanDermatophytosis, also known as Tinea infection, remains a significant interdisciplinary concern worldwide. This dermatophyte infection may be more serious in individuals with underlying somatic diseases, immunodeficiencies, endocrine disorders, or chronic illnesses. This study analyzed 313 patients with suspected dermatophytosis. Data were gathered through questionnaires and medical records were reviewed. Biological samples were cultured on Sabouraud dextrose agar, and PCR was employed to assess the genetic diversity of strains. Statistical analysis was conducted using SPSS version 26. The overall prevalence of dermatophytosis in the cohort was 30.4%. Among the cultured isolates, 73.7% were identified as <i>Microsporum canis</i>, while 26.3% were identified as <i>Trichophyton</i> species, including <i>T. mentagrophytes</i>, <i>T. tonsurans</i>, and <i>T. verrucosum</i>. Several factors were significantly associated with an increased risk of dermatophytosis, including the following: male gender (AOR = 1.97), age 1–10 years (AOR = 3.80), living in rural areas (AOR = 2.30), visiting public bathhouses (AOR = 2.32), visiting massage parlors (AOR = 1.39), contact with cats (AOR = 2.32), family history of dermatophytosis (AOR = 3.04), and sexual contact with an infected or unknown partner (AOR = 3.08). Dermatophytosis was identified in approximately one third of the patients by culture (30.4%), with the risk heightened in individuals under 10 years old (43.6%), those living in rural areas (33.3%), and those with a family history of dermatophytosis (35.7%) or close contact with cats (39.4%). The findings underscore the need for strengthened preventive measures and targeted diagnostics, particularly among high-risk groups.https://www.mdpi.com/2309-608X/11/1/65dermatophytosistineadermatophytesmycological profilerisk factorsKazakhstan |
| spellingShingle | Alma Aimoldina Ainura Smagulova Gulnar Batpenova Nellie Konnikov Togzhan Algazina Zulfiya Jetpisbayeva Dinara Azanbayeva Darkhan Amantayev Vladimir Kiyan Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan Journal of Fungi dermatophytosis tinea dermatophytes mycological profile risk factors Kazakhstan |
| title | Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan |
| title_full | Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan |
| title_fullStr | Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan |
| title_full_unstemmed | Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan |
| title_short | Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan |
| title_sort | mycological profile and associated factors among patients with dermatophytosis in astana kazakhstan |
| topic | dermatophytosis tinea dermatophytes mycological profile risk factors Kazakhstan |
| url | https://www.mdpi.com/2309-608X/11/1/65 |
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