Real-world FDA database analysis unveiling cardiovascular adverse events associated with bispecific T cell engagers in multip myeloma

Real-world FDA database analysis unveiling cardiovascular adverse events associated with bispecific T cell engagers in multip myeloma

Abstract Our study aimed to analyze the reported cardiovascular AEs (CVAEs) associated with approved bispecific T-cell engagers (BiTEs) for multiple myeloma (MM), providing insights that could guide safer clinical use of BiTEs. Data were obtained from the FDA Adverse Event Reporting System (FAERS) d...

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Bibliographic Details
Main Authors: Chang Shan, Yanli Zhang, Xinxin Zhang, Lu Li, Yanwei Chen, Ying Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Recurrent or refractory multiple myeloma
Bispecific T-cell engagers
Cardiovascular adverse events
Cardio-oncology
Faers databases
Online Access:https://doi.org/10.1038/s41598-025-03391-z
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