Recent advances of the role of Prrx1 in bone development and bone remodeling

As a marker of mesenchymal cells, the transcription factor paired related homeobox 1 (Prrx1) not only participates in the bone development process during the embryonic period, but also plays a role in the adjustment of the body's bone homeostasis and the repair process after injury in adulthood...

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Main Authors: FENG Xi, WANG Zuolin
Format: Article
Language:zho
Published: Editorial Office of Journal of Oral and Maxillofacial Surgery 2023-10-01
Series:Kouqiang hemian waike zazhi
Subjects:
Online Access:https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2023.05.010
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author FENG Xi
WANG Zuolin
author_facet FENG Xi
WANG Zuolin
author_sort FENG Xi
collection DOAJ
description As a marker of mesenchymal cells, the transcription factor paired related homeobox 1 (Prrx1) not only participates in the bone development process during the embryonic period, but also plays a role in the adjustment of the body's bone homeostasis and the repair process after injury in adulthood. Prrx1+ cells are a subpopulation of the body's mesenchymal cells, which are believed to be involved in the development and formation of long bones and skulls as osteogenic precursor cells. This article reviews the role and influence of Prrx1 and Prrx1+ cells in bone development and bone remodeling.
format Article
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institution Kabale University
issn 1005-4979
language zho
publishDate 2023-10-01
publisher Editorial Office of Journal of Oral and Maxillofacial Surgery
record_format Article
series Kouqiang hemian waike zazhi
spelling doaj-art-30e9c31faa4e40a4a3b41a0d969e860f2025-08-25T06:10:21ZzhoEditorial Office of Journal of Oral and Maxillofacial SurgeryKouqiang hemian waike zazhi1005-49792023-10-0133533633810.12439/kqhm.1005-4979.2023.05.010Recent advances of the role of Prrx1 in bone development and bone remodelingFENG Xi0WANG Zuolin1Department of Implantology, Stomatological Hospital and Dental School of Tongji University, ShanghaiEngineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072, ChinaDepartment of Implantology, Stomatological Hospital and Dental School of Tongji University, ShanghaiEngineering Research Center of Tooth Restoration and Regeneration, Shanghai 200072, ChinaAs a marker of mesenchymal cells, the transcription factor paired related homeobox 1 (Prrx1) not only participates in the bone development process during the embryonic period, but also plays a role in the adjustment of the body's bone homeostasis and the repair process after injury in adulthood. Prrx1+ cells are a subpopulation of the body's mesenchymal cells, which are believed to be involved in the development and formation of long bones and skulls as osteogenic precursor cells. This article reviews the role and influence of Prrx1 and Prrx1+ cells in bone development and bone remodeling.https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2023.05.010paired related homeobox 1prrx1+ cellsbone developmentbone remodeling
spellingShingle FENG Xi
WANG Zuolin
Recent advances of the role of Prrx1 in bone development and bone remodeling
Kouqiang hemian waike zazhi
paired related homeobox 1
prrx1+ cells
bone development
bone remodeling
title Recent advances of the role of Prrx1 in bone development and bone remodeling
title_full Recent advances of the role of Prrx1 in bone development and bone remodeling
title_fullStr Recent advances of the role of Prrx1 in bone development and bone remodeling
title_full_unstemmed Recent advances of the role of Prrx1 in bone development and bone remodeling
title_short Recent advances of the role of Prrx1 in bone development and bone remodeling
title_sort recent advances of the role of prrx1 in bone development and bone remodeling
topic paired related homeobox 1
prrx1+ cells
bone development
bone remodeling
url https://journal06.magtech.org.cn/Jweb_joms/EN/10.12439/kqhm.1005-4979.2023.05.010
work_keys_str_mv AT fengxi recentadvancesoftheroleofprrx1inbonedevelopmentandboneremodeling
AT wangzuolin recentadvancesoftheroleofprrx1inbonedevelopmentandboneremodeling