Pharmacokinetic/pharmacodynamic modeling in plasma and milk and Monte Carlo simulations of marbofloxacin against Staphylococcus aureus and Mycoplasma agalactiae in lactating sheep

Pharmacokinetic/pharmacodynamic modeling in plasma and milk and Monte Carlo simulations of marbofloxacin against Staphylococcus aureus and Mycoplasma agalactiae in lactating sheep

ABSTRACT: In livestock ruminants such as sheep, different infectious diseases such as mastitis or contagious agalactia are originated from pathogens as Staphylococcus aureus and Mycoplasma agalactiae. Fluoroquinolones are authorized in dairy animals, including their extralabel use, as an alternative...

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Bibliographic Details
Main Authors: J.M. Serrano-Rodríguez, E. Fernández-Varón, P. Muñoz-Rascón, R. Morón, X. Díaz-Villamarín, C. de la Fe, C. Cárceles-García, C.M. Cárceles-Rodríguez
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Journal of Dairy Science
Subjects:
marbofloxacin
sheep
Monte Carlo simulations
pharmacokinetics
milk
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030225001420
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